Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9DBK0 Acot12 Acetyl-coenzyme A thioesterase (EC 3.1.2.1) … Mus musculus (Mouse) 556 aa

Protein Details: Q9DBK0 (Acot12)

Protein Information
AccessionQ9DBK0
Protein NamesAcetyl-coenzyme A thioesterase (EC 3.1.2.1) (Acyl-CoA thioester hydrolase 12) (Acyl-coenzyme A thioesterase 12) (Acyl-CoA thioesterase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1)
Gene SymbolAcot12
OrganismMus musculus (Mouse)
Length556 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MESMVAPGEV11LMSQAIQPAH21ADSRGELSAG31QLLKWMDTTA41CLAAEKHAGI
51-10051SCVTASMDDI61LFEDTARIGQ71IITIRAKVTR81AFSTSMEISI91KVIVQDKFTG
101-150101IQKLLCVAFS111TFVAKPVGKE121KVHLKPVLLQ131TEQEQVEHNL141ASERRKVRLQ
151-200151HENTFNNIMK161ESSRFSDSIC171NEEEGTATTM181GTSVQSIELV191LPPHANHHGN
201-250201TFGGQIMAWM211ETVATISASR221LCHGHPFLKS231VDMFKFRGPS241TVGDRLVFSA
251-300251IVNNTFQNSV261EVGVRVEAFD271CQEWAEGQGR281HINSAFLIYN291AVDDQEKLIT
301-350301FPRIQPISKD311DFRRYQGAIA321RRRIRLGRKY331VISHKKEVPL341SAQWDISKKG
351-400351SLSNTNVEAL361KNLASKSGWE371ITTTLEKIKI381YTLEEQDAIS391VKVEKLVGSP
401-450401AHIAYHLLSD411LTKRPLWDPH421YISCEVIDQV431SEDDQIYYIT441CSVVNGDKPK
451-500451DFVVLVSRRK461PLKDNNTYTV471ALRSVVLPSV481PSSPQYIRSE491VICAGFLIQA
501-550501VDSNSCTVTY511LNQMSDSILP521YFAGNIGGWS531KSIEEAAASC541IKFIENATPD
551-556551GLKSVL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 Hotdog acyl-CoA thioesterase (ACOT)-type domain Hotdog Thioesterase Cytosolic acyl coenzyme A thioester hydrolase HotDog domain superfamily - -
Deep-Palm: 0.94
52 - - -
Deep-Palm: 0.86
106 - - -
GPS-Palm: 0.92
Deep-Palm: 0.95
170 - - -
Deep-Palm: 0.16
222 - - -
Deep-Palm: 0.57
271 - - -
Deep-Palm: 0.55
424 - - -
Deep-Palm: 0.22
441 - - -
Deep-Palm: 0.36
493 - - -
Deep-Palm: 0.29
506 - - -
Deep-Palm: 0.11
540 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine