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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9DCC4 Pycr3 Pyrroline-5-carboxylate reductase 3 (P5C reductase … Mus musculus (Mouse) 274 aa

Protein Details: Q9DCC4 (Pycr3)

Protein Information
AccessionQ9DCC4
Protein NamesPyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein)
Gene SymbolPycr3
OrganismMus musculus (Mouse)
Length274 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAATMSEPRR11VGFVGAGRMA21EAIARGLIQA31GKVEAKQVLA41SAPTDNNLCH
51-10051FRALGCQTTH61SNHEVLQNCP71LVIFATKPQV81LPTVLAEVAP91IVTTEHIIVS
101-150101VAAGISLSTM111EGLLPPNTRV121LRVSPNLPCV131VQEGAMVMAR141GHHAGNDDAE
151-200151LLQNLLEACG161QCIEVPESYV171DIHTGLSGSG181VAFVCTFSEA191LAEGAIKMGM
201-250201PSGLAHRIAA211QTLLGTAKML221QQEGKHPAQL231RTDVLTPAGT241TIHGLHALER
251-274251GGFRAATMSA261VEAATCRAKE271LSKK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
49 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Forebrain (28680068)
brain (39008777)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.69
56 - - -
Deep-Palm: 0.14
69 - - -
Deep-Palm: 0.88
129 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.94
159 - - -
Deep-Palm: 0.90
162 - - -
Deep-Palm: 0.94
185 - - -
Deep-Palm: 0.97
266 SWISSPALM DBPTM CYSMODDB Pyrroline-5-carboxylate reductase dimerisation
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.26
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.833
5
Liver
Specificity: 0.278
5/5 (100.0%)
1
Testis
Specificity: 0.056
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.667
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine