Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9ESN6 | Trim2 | Tripartite motif-containing protein 2 (EC … | Mus musculus (Mouse) | 744 aa |
Protein Details: Q9ESN6 (Trim2)
Protein Information
| Accession | Q9ESN6 |
|---|---|
| Protein Names | Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (Neural activity-related RING finger protein) (RING-type E3 ubiquitin transferase TRIM2) |
| Gene Symbol | Trim2 |
| Organism | Mus musculus (Mouse) |
| Length | 744 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASEGASIPS11PVVRQIDKQF21LICSICLERY31KNPKVLPCLH41TFCERCLQNY
51-10051IPAHSLTLSC61PVCRQTSILP71EKGVAALQNN81FFITNLMDVL91QRTPGSNGED
101-150101SSILETVTAV111AAGKPLSCPN121HDGNVMEFYC131QSCETAMCRE141CTEGEHAEHP
151-200151TVPLKDVVEQ161HKASLQVQLD171AVNKRLPEID181SALQFISEII191HQLTNQKASI
201-250201VDDIHSTFDE211LQKTLNVRKS221VLLMELEVNY231GLKHKVLQSQ241LDTLLQGQES
251-300251IKSCSNFTAQ261ALNHGTETEV271LLVKKQMSEK281LNELADQDFP291LHPRENDQLD
301-350301FIVETEGLKK311SIHNLGTILT321TNAVASETVA331TGEGLRQTII341GQPMSVTITT
351-400351KDKDGELCKT361GNAYLTAELS371TPDGSVADGE381ILDNKNGTYE391FLYTVQKEGD
401-450401FTLSLRLYDQ411HIRGSPFKLK421VIRSADVSPT431TEGVKRRVKS441PGSGHVKQKA
451-500451VKRPASMYST461GKRKENPIED471DLIFRVGTKG481RNKGEFTNLQ491GVAASTSGKI
501-550501LIADSNNQCV511QIFSNDGQFK521SRFGIRGRSP531GQLQRPTGVA541VHPSGDIIIA
551-600551DYDNKWVSIF561SNDGKFKTKI571GSGKLMGPKG581VSVDRNGHII591VVDNKACCVF
601-650601IFQPNGKIVT611RFGSRGNGDR621QFAGPHFAAV631NSNNEIIITD641FHNHSVKVFN
651-700651QEGEFMLKFG661SNGEGNGQFN671APTGVAVDSN681GNIIVADWGN691SRIQVFDGSG
701-744701SFLSYINTSA711DPLYGPQGLA721LTSDGHVVVA731DSGNHCFKVY741RYLQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 23 | Zinc finger, RING-type, eukaryotic Zinc finger, RING/FYVE/PHD-type TRIM45/56/19-like Zinc finger, RING-type RING/U-box | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.41
|
|
| 26 | Zinc finger, RING-type, eukaryotic Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type TRIM45/56/19-like RING/U-box | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.46
|
|
| 38 | Zinc finger, RING-type, eukaryotic Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type TRIM45/56/19-like RING/U-box | - |
Brain
(35358180)
|
Deep-Palm: 0.44
|
|
| 43 | Zinc finger, RING-type, eukaryotic Zinc finger, RING/FYVE/PHD-type TRIM45/56/19-like Zinc finger, RING-type RING/U-box | - |
Brain
(35358180)
|
Deep-Palm: 0.21
|
|
| 46 | TRIM45/56/19-like RING/U-box Zinc finger, RING/FYVE/PHD-type | - |
Brain
(35358180)
|
Deep-Palm: 0.18
|
|
| 60 | - | - | - |
Deep-Palm: 0.55
|
|
| 63 | - | - | - |
Deep-Palm: 0.84
|
|
| 118 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.29
|
|
| 130 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.02
|
|
| 133 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.02
|
|
| 138 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.02
|
|
| 141 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.04
|
|
| 254 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.93
|
|
| 358 | - | - | - |
Deep-Palm: 0.93
|
|
| 509 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.38
|
|
| 597 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.28
|
|
| 598 | SWISSPALM DBPTM CYSMODDB | NHL repeat |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.93
Deep-Palm: 0.34
|
| 736 | - | - | - |
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Brain
Specificity: 0.100
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.900
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.