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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9EST1 Gsdma Gasdermin-A (Gasdermin-1) (Gasdermin-A1) [Cleaved into: … Mus musculus (Mouse) 446 aa

Protein Details: Q9EST1 (Gsdma)

Protein Information
AccessionQ9EST1
Protein NamesGasdermin-A (Gasdermin-1) (Gasdermin-A1) [Cleaved into: Gasdermin-A, N-terminal (GSDMA-NT); Gasdermin-A, C-terminal (GSDMA-CT)]
Gene SymbolGsdma
OrganismMus musculus (Mouse)
Length446 aa
IsoformsNo isoforms
Related PMIDs 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTMFENVTRA11LARQLNPRGD21LTPLDSLIDF31KRFHPFCLVL41RKRKSTLFWG
51-10051ARYVHTDYTL61LDVLEPGSSP71SDPTDSGNFS81FKNMLDARVE91GDVDVPKTVK
101-150101VKGTAGLSRS111STLEVQTLSV121APTALENLHK131ERKLSADHPF141LKEMRERGEN
151-200151LYVVMEVVET161LQEVTLERAG171KAEGCFSLPF181FAPLGLQGSV191NHKEAVTIPK
201-250201GCVLAYRVRQ211LMVNGKDEWG221IPHICNDSMQ231TFPPGEKPGE241GKFILIQASD
251-300251VGEMHEDFKT261LKEEVQRETQ271EVEKLSPVGR281SSLLTSLSHL291LGKKKELQDL
301-350301EQTLEGALDK311GHEVTLEALP321KDVLLSKDAM331DAILYFLGAL341TVLSEAQQKL
351-400351LVKSLEKKIL361PVQLKLVEST371MEKNFLQDKE381GVFPLQPDLL391SSLGEEELIL
401-446401TEALVGLSGL411EVQRSGPQYT421WDPDTLPHLC431ALYAGLSLLQ441LLSKNS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
37 SWISSPALM DBPTM CYSMODDB Gasdermin Gasdermin pore forming domain Gasdermin, pore forming domain - -
GPS-Palm: 0.94
Deep-Palm: 0.93
175 - - -
Deep-Palm: 0.98
202 - - -
GPS-Palm: 0.95
Deep-Palm: 0.96
225 - - -
Deep-Palm: 0.07
430 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine