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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9GZV1 ANKRD2 Ankyrin repeat domain-containing protein 2 … Homo sapiens (Human) 360 aa

Protein Details: Q9GZV1 (ANKRD2)

Protein Information
AccessionQ9GZV1
Protein NamesAnkyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp)
Gene SymbolANKRD2
OrganismHomo sapiens (Human)
Length360 aa
IsoformsNo isoforms
Related PMIDs 33636221
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAKAPSWAGV11GALAYKAPEA21LWPAEAVMDG31TMEDSEAVQR41ATALIEQRLA
51-10051QEEENEKLRG61DARQKLPMDL71LVLEDEKHHG81AQSAALQKVK91GQERVRKTSL
101-150101DLRREIIDVG111GIQNLIELRK121KRKQKKRDAL131AASHEPPPEP141EEITGPVDEE
151-200151TFLKAAVEGK161MKVIEKFLAD171GGSADTCDQF181RRTALHRASL191EGHMEILEKL
201-250201LDNGATVDFQ211DRLDCTAMHW221ACRGGHLEVV231KLLQSHGADT241NVRDKLLSTP
251-300251LHVAVRTGQV261EIVEHFLSLG271LEINARDREG281DTALHDAVRL291NRYKIIKLLL
301-350301LHGADMMTKN311LAGKTPTDLV321QLWQADTRHA331LEHPEPGAEH341NGLEGPNDSG
351-360351RETPQPVPAQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
177 - - -
GPS-Palm: 0.73
Deep-Palm: 0.94
215 - - -
Deep-Palm: 0.38
222 - - -
Deep-Palm: 0.76
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
63 R → C 0.001887 SNP Missense Mutation UCEC
181 R → C 0.002427 SNP Missense Mutation BLCA