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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9H0Q0 CYRIA; FAM49A CYFIP-related Rac1 interactor A (Protein … Homo sapiens (Human) 323 aa

Protein Details: Q9H0Q0 (CYRIA)

Protein Information
Accession Q9H0Q0
Protein Names CYFIP-related Rac1 interactor A (Protein CYRIA)
Gene Symbol CYRIA; FAM49A
Organism Homo sapiens (Human)
Length 323 aa
Isoforms No isoforms
Related PMIDs 24357059 29575903 31251020 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.921
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.921
35/46 (76.1%)
1
HeLa cells
Specificity: 0.026
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.026
1/2 (50.0%)
1
Cerebral cortex
Specificity: 0.026
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGNLLKVLTR11EIENYPHFFL21DFENAQPTEG31EREIWNQISA41VLQDSESILA
51-10051DLQAYKGAGP61EIRDAIQNPN71DIQLQEKAWN81AVCPLVVRLK91RFYEFSIRLE
101-150101KALQSLLESL111TCPPYTPTQH121LEREQALAKE131FAEILHFTLR141FDELKMRNPA
151-200151IQNDFSYYRR161TISRNRINNM171HLDIENEVNN181EMANRMSLFY191AEATPMLKTL
201-250201SNATMHFVSE211NKTLPIENTT221DCLSTMTSVC231KVMLETPEYR241SRFTSEETLM
251-300251FCMRVMVGVI261ILYDHVHPVG271AFCKTSKIDM281KGCIKVLKEQ291APDSVEGLLN
301-323301ALRFTTKHLN311DESTSKQIRA321MLQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
83 Prediction (High) - -
222 Prediction (Low) - -
252 Prediction (Medium) - -
273 Prediction (Medium) - -
283 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
112 C → Y 0.001887 SNP Missense Mutation UCEC
166 R → C 0.001969 SNP Missense Mutation HNSC
222 C → S 0.001764 SNP Missense Mutation LUAD
276 S → C 0.001014 SNP Missense Mutation BRCA
283 C → C 0.001887 SNP Silent UCEC