Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H0U4 | RAB1B | Ras-related protein Rab-1B (EC 3.6.5.2) | Homo sapiens (Human) | 201 aa |
Protein Details: Q9H0U4 (RAB1B)
Protein Information
| Accession | Q9H0U4 |
|---|---|
| Protein Names | Ras-related protein Rab-1B (EC 3.6.5.2) |
| Gene Symbol | RAB1B |
| Organism | Homo sapiens (Human) |
| Length | 201 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 21076176 22496122 26876311 29733200 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNPEYDYLFK11LLLIGDSGVG21KSCLLLRFAD31DTYTESYIST41IGVDFKIRTI
51-10051ELDGKTIKLQ61IWDTAGQERF71RTITSSYYRG81AHGIIVVYDV91TDQESYANVK
101-150101QWLQEIDRYA111SENVNKLLVG121NKSDLTTKKV131VDNTTAKEFA141DSLGIPFLET
151-200151SAKNATNVEQ161AFMTMAAEIK171KRMGPGAASG181GERPNLKIDS191TPVKPAGGGC
201-201201C
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 23 | SWISSPALM DBPTM CYSMODDB | Ras family Small GTPase superfamily, Rab P-loop containing nucleoside triphosphate hydrolase Transforming protein P21 ras signature Small GTPase small GTPase Rab1 family profile. | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
| 200 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
|
| 201 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.286
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.143
1/1 (100.0%)
1
EC cell
Specificity: 0.143
1/1 (100.0%)
1
frontal cortex
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 88 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 200 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 200 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |