Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H1C7 | CYSTM1 | Cysteine-rich transmembrane module-containing protein 1 | Homo sapiens (Human) | 97 aa |
Protein Details: Q9H1C7 (CYSTM1)
Protein Information
| Accession | Q9H1C7 |
|---|---|
| Protein Names | Cysteine-rich transmembrane module-containing protein 1 |
| Gene Symbol | CYSTM1 |
| Organism | Homo sapiens (Human) |
| Length | 97 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNQENPPPYP11GPGPTAPYPP21YPPQPMGPGP31MGGPYPPPQG41YPYQGYPQYG
51-9751WQGGPQEPPK61TTVYVVEDQR71RDELGPSTCL81TACWTALCCC91CLWDMLT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 79 | SWISSPALM DBPTM CYSMODDB | Cysteine-rich TM module stress tolerance | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.68
|
| 83 | SWISSPALM DBPTM CYSMODDB | Cysteine-rich TM module stress tolerance | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.43
|
| 88 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.03
|
|
| 89 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.02
|
|
| 90 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.02
|
|
| 91 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
3
CEM 174 cell
Specificity: 0.333
3/3 (100.0%)
1
LNCaP
Specificity: 0.111
1/1 (100.0%)
1
HAP1 cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 89 | C → Y | 0.002545 | SNP | Missense Mutation | GBM |