Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H2H9 | SLC38A1; ATA1; NAT2; SAT1; SNAT1 | Sodium-coupled neutral amino acid symporter … | Homo sapiens (Human) | 487 aa |
Protein Details: Q9H2H9 (SLC38A1)
Protein Information
| Accession | Q9H2H9 |
|---|---|
| Protein Names | Sodium-coupled neutral amino acid symporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1) |
| Gene Symbol | SLC38A1; ATA1; NAT2; SAT1; SNAT1 |
| Organism | Homo sapiens (Human) |
| Length | 487 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
30
LNCaP cells
Specificity: 0.600
30/46 (65.2%)
10
HAP1 cells
Specificity: 0.200
10/10 (100.0%)
6
293T cells
Specificity: 0.120
6/10 (60.0%)
4
PC3 cells
Specificity: 0.080
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MMHFKSGLEL11TELQNMTVPE21DDNISNDSND31FTEVENGQIN41SKFISDRESR
51-10051RSLTNSHLEK61KKCDEYIPGT71TSLGMSVFNL81SNAIMGSGIL91GLAFALANTG
101-150101ILLFLVLLTS111VTLLSIYSIN121LLLICSKETG131CMVYEKLGEQ141VFGTTGKFVI
151-200151FGATSLQNTG161AMLSYLFIVK171NELPSAIKFL181MGKEETFSAW191YVDGRVLVVI
201-250201VTFGIILPLC211LLKNLGYLGY221TSGFSLSCMV231FFLIVVIYKK241FQIPCIVPEL
251-300251NSTISANSTN261ADTCTPKYVT271FNSKTVYALP281TIAFAFVCHP291SVLPIYSELK
301-350301DRSQKKMQMV311SNISFFAMFV321MYFLTAIFGY331LTFYDNVQSD341LLHKYQSKDD
351-400351ILILTVRLAV361IVAVILTVPV371LFFTVRSSLF381ELAKKTKFNL391CRHTVVTCIL
401-450401LVVINLLVIF411IPSMKDIFGV421VGVTSANMLI431FILPSSLYLK441ITDQDGDKGT
451-487451QRIWAALFLG461LGVLFSLVSI471PLVIYDWACS481SSSDEGH
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 125 | Prediction (Low) | - | - |
| 131 | Prediction (Medium) | - | - |
| 210 | Prediction (Medium) | - | - |
| 245 | Prediction (Low) | - | - |
| 288 | CYSMODDB SWISSPALM DBPTM | Transmembrane amino acid transporter protein | - |
| 391 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | 37611173 |
| 398 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 130 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 264 | C → C | 0.002288 | SNP | Silent | STAD |
| 307 | M → Cfs*18 | 0.002288 | DEL | Frame Shift Del | STAD |
| 307 | M → Cfs*18 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 376 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |