Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H2P0 | ADNP; ADNP1; KIAA0784 | Activity-dependent neuroprotector homeobox protein (Activity-dependent … | Homo sapiens (Human) | 1102 aa |
Protein Details: Q9H2P0 (ADNP)
Protein Information
| Accession | Q9H2P0 |
|---|---|
| Protein Names | Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein) |
| Gene Symbol | ADNP; ADNP1; KIAA0784 |
| Organism | Homo sapiens (Human) |
| Length | 1102 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.837
36/46 (78.3%)
4
HAP1 cells
Specificity: 0.093
4/10 (40.0%)
2
PC3 cells
Specificity: 0.047
2/4 (50.0%)
1
U937 cells
Specificity: 0.023
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFQLPVNNLG11SLRKARKTVK21KILSDIGLEY31CKEHIEDFKQ41FEPNDFYLKN
51-10051TTWEDVGLWD61PSLTKNQDYR71TKPFCCSACP81FSSKFFSAYK91SHFRNVHSED
101-150101FENRILLNCP111YCTFNADKKT121LETHIKIFHA131PNASAPSSSL141STFKDKNKND
151-200151GLKPKQADSV161EQAVYYCKKC171TYRDPLYEIV181RKHIYREHFQ191HVAAPYIAKA
201-250201GEKSLNGAVP211LGSNAREESS221IHCKRCLFMP231KSYEALVQHV241IEDHERIGYQ
251-300251VTAMIGHTNV261VVPRSKPLML271IAPKPQDKKS281MGLPPRIGSL291ASGNVRSLPS
301-350301QQMVNRLSIP311KPNLNSTGVN321MMSSVHLQQN331NYGVKSVGQG341YSVGQSMRLG
351-400351LGGNAPVSIP361QQSQSVKQLL371PSGNGRSYGL381GSEQRSQAPA391RYSLQSANAS
401-450401SLSSGQLKSP411SLSQSQASRV421LGQSSSKPAA431AATGPPPGNT441SSTQKWKICT
451-500451ICNELFPENV461YSVHFEKEHK471AEKVPAVANY481IMKIHNFTSK491CLYCNRYLPT
501-550501DTLLNHMLIH511GLSCPYCRST521FNDVEKMAAH531MRMVHIDEEM541GPKTDSTLSF
551-600551DLTLQQGSHT561NIHLLVTTYN571LRDAPAESVA581YHAQNNPPVP591PKPQPKVQEK
601-650601ADIPVKSSPQ611AAVPYKKDVG621KTLCPLCFSI631LKGPISDALA641HHLRERHQVI
651-700651QTVHPVEKKL661TYKCIHCLGV671YTSNMTASTI681TLHLVHCRGV691GKTQNGQDKT
701-750701NAPSRLNQSP711SLAPVKRTYE721QMEFPLLKKR731KLDDDSDSPS741FFEEKPEEPV
751-800751VLALDPKGHE761DDSYEARKSF771LTKYFNKQPY781PTRREIEKLA791ASLWLWKSDI
801-850801ASHFSNKRKK811CVRDCEKYKP821GVLLGFNMKE831LNKVKHEMDF841DAEWLFENHD
851-900851EKDSRVNASK861TADKKLNLGK871EDDSSSDSFE881NLEEESNESG891SPFDPVFEVE
901-950901PKISNDNPEE911HVLKVIPEDA921SESEEKLDQK931EDGSKYETIH941LTEEPTKLMH
951-1000951NASDSEVDQD961DVVEWKDGAS971PSESGPGSQQ981VSDFEDNTCE991MKPGTWSDES
1001-10501001SQSEDARSSK1011PAAKKKATMQ1021GDREQLKWKN1031SSYGKVEGFW1041SKDQSQWKNA
1051-11001051SENDERLSNP1061QIEWQNSTID1071SEDGEQFDNM1081TDGVAEPMHG1091SLAGVKLSSQ
1101-11021101QA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 31 | Prediction (Low) | - | - |
| 75 | Prediction (Low) | - | - |
| 76 | Prediction (Medium) | - | - |
| 79 | Prediction (Medium) | - | - |
| 109 | Prediction (Medium) | - | - |
| 112 | Prediction (Low) | - | - |
| 223 | Prediction (Low) | - | - |
| 226 | Prediction (Low) | - | - |
| 449 | Prediction (Low) | - | - |
| 452 | Prediction (Low) | - | - |
| 517 | Prediction (Low) | - | - |
| 624 | Prediction (Medium) | - | - |
| 627 | Prediction (High) | - | - |
| 667 | Prediction (Low) | - | - |
| 687 | Prediction (Low) | - | - |
| 811 | Prediction (Low) | - | - |
| 815 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 87 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 94 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 185 | Y → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 246 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 332 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 401 | S → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 438 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 449 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 491 | C → C | 0.001887 | SNP | Silent | UCEC |
| 491 | C → G | 0.001887 | SNP | Missense Mutation | UCEC |
| 493 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 813 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 818 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 989 | C → C | 0.001887 | SNP | Silent | UCEC |
| 1031 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 1056 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1058 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |