Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H2U9 | ADAM7 | Disintegrin and metalloproteinase domain-containing protein … | Homo sapiens (Human) | 754 aa |
Protein Details: Q9H2U9 (ADAM7)
Protein Information
| Accession | Q9H2U9 |
|---|---|
| Protein Names | Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Sperm maturation-related glycoprotein GP-83) |
| Gene Symbol | ADAM7 |
| Organism | Homo sapiens (Human) |
| Length | 754 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLPGCIFLMI11LLIPQVKEKF21ILGVEGQQLV31RPKKLPLIQK41RDTGHTHDDD
51-10051ILKTYEEELL61YEIKLNRKTL71VLHLLRSREF81LGSNYSETFY91SMKGEAFTRH
101-150101PQIMDHCFYQ111GSIVHEYDSA121ASISTCNGLR131GFFRINDQRY141LIEPVKYSDE
151-200151GEHLVFKYNL161RVPYGANYSC171TELNFTRKTV181PGDNESEEDS191KIKGIHDEKY
201-250201VELFIVADDT211VYRRNGHPHN221KLRNRIWGMV231NFVNMIYKTL241NIHVTLVGIE
251-300251IWTHEDKIEL261YSNIETTLLR271FSFWQEKILK281TRKDFDHVVL291LSGKWLYSHV
301-350301QGISYPGGMC311LPYYSTSIIK321DLLPDTNIIA331NRMAHQLGHN341LGMQHDEFPC
351-400351TCPSGKCVMD361SDGSIPALKF371SKCSQNQYHQ381YLKDYKPTCM391LNIPFPYNFH
401-450401DFQFCGNKKL411DEGEECDCGP421AQECTNPCCD431AHTCVLKPGF441TCAEGECCES
451-500451CQIKKAGSIC461RPAKDECDFP471EMCTGHSPAC481PKDQFRVNGF491PCKNSEGYCF
501-550501MGKCPTREDQ511CSELFDDEAI521ESHDICYKMN531TKGNKFGYCK541NKENRFLPCE
551-600551EKDVRCGKIY561CTGGELSSLL571GEDKTYHLKD581PQKNATVKCK591TIFLYHDSTD
601-650601IGLVASGTKC611GEGMVCNNGE621CLNMEKVYIS631TNCPSQCNEN641PVDGHGLQCH
651-700651CEEGQAPVAC661EETLHVTNIT671ILVVVLVLVI681VGIGVLILLV691RYRKCIKLKQ
701-750701VQSPPTETLG711VENKGYFGDE721QQIRTEPILP731EIHFLNKPAS741KDSRGIADPN
751-754751QSAK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.04
|
|
| 107 | - | - | - |
Deep-Palm: 0.08
|
|
| 126 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.37
|
|
| 170 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.61
|
|
| 310 | - | - | - |
Deep-Palm: 0.43
|
|
| 350 | - | - | - |
Deep-Palm: 0.03
|
|
| 352 | - | - | - |
Deep-Palm: 0.04
|
|
| 357 | - | - | - |
Deep-Palm: 0.06
|
|
| 373 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.16
|
|
| 389 | - | - | - |
Deep-Palm: 0.02
|
|
| 405 | - | - | - |
Deep-Palm: 0.03
|
|
| 416 | - | - | - |
Deep-Palm: 0.04
|
|
| 418 | - | - | - |
Deep-Palm: 0.04
|
|
| 424 | - | - | - |
Deep-Palm: 0.10
|
|
| 428 | - | - | - |
Deep-Palm: 0.03
|
|
| 429 | - | - | - |
Deep-Palm: 0.03
|
|
| 434 | - | - | - |
Deep-Palm: 0.04
|
|
| 442 | - | - | - |
Deep-Palm: 0.10
|
|
| 447 | - | - | - |
Deep-Palm: 0.13
|
|
| 448 | - | - | - |
Deep-Palm: 0.21
|
|
| 451 | - | - | - |
Deep-Palm: 0.37
|
|
| 460 | SWISSPALM DBPTM CYSMODDB | Disintegrin | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.05
|
| 467 | - | - | - |
Deep-Palm: 0.07
|
|
| 473 | - | - | - |
Deep-Palm: 0.05
|
|
| 480 | - | - | - |
Deep-Palm: 0.02
|
|
| 492 | - | - | - |
Deep-Palm: 0.11
|
|
| 499 | - | - | - |
Deep-Palm: 0.10
|
|
| 504 | - | - | - |
Deep-Palm: 0.06
|
|
| 511 | - | - | - |
Deep-Palm: 0.04
|
|
| 526 | - | - | - |
Deep-Palm: 0.05
|
|
| 539 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.07
|
|
| 549 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.24
|
|
| 556 | - | - | - |
Deep-Palm: 0.93
|
|
| 561 | - | - | - |
Deep-Palm: 0.93
|
|
| 589 | - | - | - |
Deep-Palm: 0.33
|
|
| 610 | - | - | - |
Deep-Palm: 0.30
|
|
| 616 | - | - | - |
Deep-Palm: 0.65
|
|
| 621 | - | - | - |
Deep-Palm: 0.06
|
|
| 633 | - | - | - |
Deep-Palm: 0.04
|
|
| 637 | - | - | - |
Deep-Palm: 0.02
|
|
| 649 | - | - | - |
Deep-Palm: 0.05
|
|
| 651 | - | - | - |
Deep-Palm: 0.04
|
|
| 660 | - | - | - |
Deep-Palm: 0.14
|
|
| 695 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 31 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 31 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 107 | C → C | 0.002506 | SNP | Silent | COAD |
| 186 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 213 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 310 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 357 | C → C | 0.002506 | SNP | Silent | COAD |
| 389 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 434 | C → C | 0.001887 | SNP | Silent | UCEC |
| 498 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 499 | C → C | 0.001887 | SNP | Silent | UCEC |
| 526 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 633 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 691 | R → C | 0.008565 | SNP | Missense Mutation | SKCM |
| 695 | C → F | 0.002288 | SNP | Missense Mutation | STAD |
| 649* | C → ? | 0.002545 | SNP | Nonsense Mutation | GBM |