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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9H361 PABPC3 Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding … Homo sapiens (Human) 631 aa

Protein Details: Q9H361 (PABPC3)

Protein Information
AccessionQ9H361
Protein NamesPolyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)
Gene SymbolPABPC3
OrganismHomo sapiens (Human)
Length631 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNPSTPSYPT11ASLYVGDLHP21DVTEAMLYEK31FSPAGPILSI41RICRDLITSG
51-10051SSNYAYVNFQ61HTKDAEHALD71TMNFDVIKGK81PVRIMWSQRD91PSLRKSGVGN
101-150101IFVKNLDKSI111NNKALYDTVS121AFGNILSCNV131VCDENGSKGY141GFVHFETHEA
151-200151AERAIKKMNG161MLLNGRKVFV171GQFKSRKERE181AELGARAKEF191PNVYIKNFGE
201-250201DMDDERLKDL211FGKFGPALSV221KVMTDESGKS231KGFGFVSFER241HEDAQKAVDE
251-300251MNGKELNGKQ261IYVGRAQKKV271ERQTELKRTF281EQMKQDRITR291YQVVNLYVKN
301-350301LDDGIDDERL311RKAFSPFGTI321TSAKVMMEGG331RSKGFGFVCF341SSPEEATKAV
351-400351TEMNGRIVAT361KPLYVALAQR371KEERQAYLTN381EYMQRMASVR391AVPNQRAPPS
401-450401GYFMTAVPQT411QNHAAYYPPS421QIARLRPSPR431WTAQGARPHP441FQNKPSAIRP
451-500451GAPRVPFSTM461RPASSQVPRV471MSTQRVANTS481TQTVGPRPAA491AAAAAATPAV
501-550501RTVPRYKYAA511GVRNPQQHRN521AQPQVTMQQL531AVHVQGQETL541TASRLASAPP
551-600551QKQKQMLGER561LFPLIQAMHP571TLAGKITGML581LEIDNSELLY591MLESPESLRS
601-631601KVDEAVAVLQ611AHQAKEATQK621AVNSATGVPT631V
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
43 RNA-binding domain superfamily Nucleotide-binding alpha-beta plait domain superfamily RNA recognition motif domain - -
GPS-Palm: 0.85
Deep-Palm: 0.81
128 - - -
Deep-Palm: 0.50
132 - - -
Deep-Palm: 0.09
339 SWISSPALM DBPTM CYSMODDB RNA recognition motif - -
GPS-Palm: 0.80
Deep-Palm: 0.89
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
50 G → C 0.001969 SNP Missense Mutation HNSC
54 Y → C 0.002288 SNP Missense Mutation STAD
83 R → C 0.001887 SNP Missense Mutation UCEC
89 R → C 0.002288 SNP Missense Mutation STAD
206 R → C 0.001887 SNP Missense Mutation UCEC
501 R → C 0.003774 SNP Missense Mutation UCEC
513 R → C 0.007299 SNP Missense Mutation READ
513 R → C 0.003774 SNP Missense Mutation UCEC
519 R → C 0.002506 SNP Missense Mutation COAD
562 F → C 0.002545 SNP Missense Mutation GBM