Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H3K2 | GHITM; DERP2; MICS1; TMBIM5; My021; UNQ244/PRO281 | Growth hormone-inducible transmembrane protein (Dermal … | Homo sapiens (Human) | 345 aa |
Protein Details: Q9H3K2 (GHITM)
Protein Information
| Accession | Q9H3K2 |
|---|---|
| Protein Names | Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5) |
| Gene Symbol | GHITM; DERP2; MICS1; TMBIM5; My021; UNQ244/PRO281 |
| Organism | Homo sapiens (Human) |
| Length | 345 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.488
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
21
LNCaP cells
Specificity: 0.488
21/46 (45.7%)
10
HAP1 cells
Specificity: 0.233
10/10 (100.0%)
10
293T cells
Specificity: 0.233
10/10 (100.0%)
1
PC3 cells
Specificity: 0.023
1/4 (25.0%)
1
CEMx174 cells
Specificity: 0.023
1/3 (33.3%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLAARLVCLR11TLPSRVFHPA21FTKASPVVKN31SITKNQWLLT41PSREYATKTR
51-10051IGIRRGRTGQ61ELKEAALEPS71MEKIFKIDQM81GRWFVAGGAA91VGLGALCYYG
101-150101LGLSNEIGAI111EKAVIWPQYV121KDRIHSTYMY131LAGSIGLTAL141SAIAISRTPV
151-200151LMNFMMRGSW161VTIGVTFAAM171VGAGMLVRSI181PYDQSPGPKH191LAWLLHSGVM
201-250201GAVVAPLTIL211GGPLLIRAAW221YTAGIVGGLS231TVAMCAPSEK241FLNMGAPLGV
251-300251GLGLVFVSSL261GSMFLPPTTV271AGATLYSVAM281YGGLVLFSMF291LLYDTQKVIK
301-345301RAEVSPMYGV311QKYDPINSML321SIYMDTLNIF331MRVATMLATG341GNRKK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | Prediction (High) | - | - |
| 97 | Prediction (Low) | - | - |
| 235 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 25 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 99 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 323 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |