Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H3K2 | GHITM | Growth hormone-inducible transmembrane protein (Dermal … | Homo sapiens (Human) | 345 aa |
Protein Details: Q9H3K2 (GHITM)
Protein Information
| Accession | Q9H3K2 |
|---|---|
| Protein Names | Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5) |
| Gene Symbol | GHITM |
| Organism | Homo sapiens (Human) |
| Length | 345 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 32944167 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLAARLVCLR11TLPSRVFHPA21FTKASPVVKN31SITKNQWLLT41PSREYATKTR
51-10051IGIRRGRTGQ61ELKEAALEPS71MEKIFKIDQM81GRWFVAGGAA91VGLGALCYYG
101-150101LGLSNEIGAI111EKAVIWPQYV121KDRIHSTYMY131LAGSIGLTAL141SAIAISRTPV
151-200151LMNFMMRGSW161VTIGVTFAAM171VGAGMLVRSI181PYDQSPGPKH191LAWLLHSGVM
201-250201GAVVAPLTIL211GGPLLIRAAW221YTAGIVGGLS231TVAMCAPSEK241FLNMGAPLGV
251-300251GLGLVFVSSL261GSMFLPPTTV271AGATLYSVAM281YGGLVLFSMF291LLYDTQKVIK
301-345301RAEVSPMYGV311QKYDPINSML321SIYMDTLNIF331MRVATMLATG341GNRKK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.17
|
|
| 97 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.98
|
|
| 235 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.250
2
LNCaP
Specificity: 0.250
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.250
2/2 (100.0%)
2
293T cell
Specificity: 0.250
2/2 (100.0%)
1
PC3
Specificity: 0.125
1/1 (100.0%)
1
CEM 174 cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 25 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 99 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 323 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |