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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member … Homo sapiens (Human) 167 aa

Protein Details: Q9H3Z4-2 (DNAJC5)

Protein Information
AccessionQ9H3Z4-2
Protein NamesDnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)
Gene SymbolDNAJC5
OrganismHomo sapiens (Human)
Length167 aa
Isoforms
Related PMIDs 31251020 32651440 32944167 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADQRQRSLS11TSGESLYHVL21GLDKNATSDD31IKKSYRKLAL41KYHPDKNPDN
51-10051PEAADKFKEI61NNAHAILTDA71TKRNIYDKYG81SLGLYVAEQF91GEENVNTYFV
101-150101LSSWWAKALF111VFCGLLTCCY121CCCCLCCCFN131CCCGKCKPKA141PEGEETEFYV
151-167151SPEDLEAQLQ161SDERGGH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
113 - - -
Deep-Palm: 0.30
118 - - -
GPS-Palm: 0.90
Deep-Palm: 0.26
119 - - -
GPS-Palm: 0.96
Deep-Palm: 0.30
121 - - -
GPS-Palm: 0.96
Deep-Palm: 0.27
122 - - -
GPS-Palm: 0.95
Deep-Palm: 0.23
123 - - -
GPS-Palm: 0.96
Deep-Palm: 0.21
124 - - -
GPS-Palm: 0.92
Deep-Palm: 0.15
126 - - -
GPS-Palm: 0.95
Deep-Palm: 0.24
127 - - -
GPS-Palm: 0.95
Deep-Palm: 0.34
128 - - -
GPS-Palm: 0.96
Deep-Palm: 0.44
131 - - -
GPS-Palm: 0.97
Deep-Palm: 0.38
132 - - -
GPS-Palm: 0.97
Deep-Palm: 0.31
133 - - -
GPS-Palm: 0.96
Deep-Palm: 0.23
136 - - -
Deep-Palm: 0.59
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
PC3
Specificity: 0.364
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
2
LNCaP
Specificity: 0.182
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
133 C → C 0.001887 SNP Silent UCEC