Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9H400 | LIME1 | Lck-interacting transmembrane adapter 1 (Lck-interacting … | Homo sapiens (Human) | 295 aa |
Protein Details: Q9H400 (LIME1)
Protein Information
| Accession | Q9H400 |
|---|---|
| Protein Names | Lck-interacting transmembrane adapter 1 (Lck-interacting membrane protein) (Lck-interacting molecule) |
| Gene Symbol | LIME1 |
| Organism | Homo sapiens (Human) |
| Length | 295 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 32651440 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLPVSWAPP11ALWVLGCCAL21LLSLWALCTA31CRRPEDAVAP41RKRARRQRAR
51-10051LQGSATAAEA61SLLRRTHLCS71LSKSDTRLHE81LHRGPRSSRA91LRPASMDLLR
101-150101PHWLEVSRDI111TGPQAAPSAF121PHQELPRALP131AAAATAGCAG141LEATYSNVGL
151-200151AALPGVSLAA161SPVVAEYARV171QKRKGTHRSP181QEPQQGKTEV191TPAAQVDVLY
201-250201SRVCKPKRRD211PGPTTDPLDP221KGQGAILALA231GDLAYQTLPL241RALDVDSGPL
251-295251ENVYESIREL261GDPAGRSSTC271GAGTPPASSC281PSLGRGWRPL291PASLP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | Lck-interacting transmembrane adapter 1 | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.98
|
|
| 18 | Lck-interacting transmembrane adapter 1 | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.97
|
|
| 28 | DBPTM | Lck-interacting transmembrane adapter 1 | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
| 31 | DBPTM | Lck-interacting transmembrane adapter 1 | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
| 69 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.97
|
|
| 138 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.98
|
|
| 204 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.90
|
|
| 270 | - | - | - |
Deep-Palm: 0.94
|
|
| 280 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Jurkat T cell
Specificity: 0.667
6/6 (100.0%)
3
Primary T cell
Specificity: 0.333
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 173 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 270 | C → Rfs*15 | 0.002427 | INS | Frame Shift Ins | BLCA |