Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9HA72 | CALHM2 | Calcium homeostasis modulator protein 2 … | Homo sapiens (Human) | 323 aa |
Protein Details: Q9HA72 (CALHM2)
Protein Information
| Accession | Q9HA72 |
|---|---|
| Protein Names | Calcium homeostasis modulator protein 2 (Protein FAM26B) |
| Gene Symbol | CALHM2 |
| Organism | Homo sapiens (Human) |
| Length | 323 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAALIAENFR11FLSLFFKSKD21VMIFNGLVAL31GTVGSQELFS41VVAFHCPCSP
51-10051ARNYLYGLAA61IGVPALVLFI71IGIILNNHTW81NLVAECQHRR91TKNCSAAPTF
101-150101LLLSSILGRA111AVAPVTWSVI121SLLRGEAYVC131ALSEFVDPSS141LTAREEHFPS
151-200151AHATEILARF161PCKENPDNLS171DFREEVSRRL181RYESQLFGWL191LIGVVAILVF
201-250201LTKCLKHYCS211PLSYRQEAYW221AQYRANEDQL231FQRTAEVHSR241VLAANNVRRF
251-300251FGFVALNKDD261EELIANFPVE271GTQPRPQWNA281ITGVYLYREN291QGLPLYSRLH
301-323301KWAQGLAGNG311AAPDNVEMAL321LPS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 46 | Calcium homeostasis modulator family | - | - |
Deep-Palm: 0.81
|
|
| 48 | Calcium homeostasis modulator family | - | - |
Deep-Palm: 0.83
|
|
| 86 | - | - | - |
Deep-Palm: 0.18
|
|
| 94 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.91
|
|
| 130 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.98
|
|
| 162 | - | - | - |
Deep-Palm: 0.77
|
|
| 204 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.92
|
|
| 209 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Primary T cell
Specificity: 0.800
4/4 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 31 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 105 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 124 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 162 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 178 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 248 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 249 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 298 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |