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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9HAK2 EBF2 Transcription factor COE2 (Early B-cell … Homo sapiens (Human) 575 aa

Protein Details: Q9HAK2 (EBF2)

Protein Information
AccessionQ9HAK2
Protein NamesTranscription factor COE2 (Early B-cell factor 2) (EBF-2)
Gene SymbolEBF2
OrganismHomo sapiens (Human)
Length575 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MFGIQDTLGR11GPTLKEKSLG21AEMDSVRSWV31RNVGVVDANV41AAQSGVALSR
51-10051AHFEKQPPSN61LRKSNFFHFV71LALYDRQGQP81VEIERTAFVD91FVENDKEQGN
101-150101EKTNNGTHYK111LQLLYSNGVR121TEQDLYVRLI131DSVTKQPIAY141EGQNKNPEMC
151-200151RVLLTHEVMC161SRCCEKKSCG171NRNETPSDPV181IIDRFFLKFF191LKCNQNCLKT
201-250201AGNPRDMRRF211QVVLSTTVNV221DGHVLAVSDN231MFVHNNSKHG241RRARRLDPSE
251-300251ATPCIKAISP261SEGWTTGGAM271VIIIGDNFFD281GLQVVFGTML291VWSELITPHA
301-350301IRVQTPPRHI311PGVVEVTLSY321KSKQFCKGAP331GRFIYTALNE341PTIDYGFQRL
351-400351QKVIPRHPGD361PERLAKEMLL371KRAADLVEAL381YGTPHNNQDI391ILKRAADIAE
401-450401ALYSVPRNPS411QLPALSSSPA421HSGMMGINSY431GSQLGVSISE441STQGNNQGYI
451-500451RNTSSISPRG461YSSSSTPQQS471NYSTSSNSMN481GYSNVPMANL491GVPGSPGFLN
501-550501GSPTGSPYGI511MSSSPTVGSS521STSSILPFSS531SVFPAVKQKS541AFAPVIRPQG
551-575551SPSPACSSGN561GNGFRAMTGL571VVPPM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
150 - - -
Deep-Palm: 0.10
160 SWISSPALM DBPTM CYSMODDB Transcription factor COE1 DNA-binding domain - -
GPS-Palm: 0.77
Deep-Palm: 0.28
163 - - -
Deep-Palm: 0.17
164 - - -
Deep-Palm: 0.17
169 - - -
Deep-Palm: 0.12
193 - - -
GPS-Palm: 0.82
Deep-Palm: 0.58
197 - - -
GPS-Palm: 0.78
Deep-Palm: 0.59
254 - - -
GPS-Palm: 0.67
Deep-Palm: 0.94
326 - - -
GPS-Palm: 0.87
Deep-Palm: 0.91
556 - - -
Deep-Palm: 0.90
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
78 G → C 0.001764 SNP Missense Mutation LUAD
150 C → Y 0.002288 SNP Missense Mutation STAD
164 C → C 0.005618 SNP Silent PAAD
193 C → G 0.003559 SNP Missense Mutation KIRP
254 C → Lfs*6 0.002288 INS Frame Shift Ins STAD
312 G → C 0.001887 SNP Missense Mutation UCEC
462 S → C 0.001764 SNP Missense Mutation LUAD
462 S → C 0.002033 SNP Missense Mutation LUSC