Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9JII6 | Akr1a1 | Aldo-keto reductase family 1 member … | Mus musculus (Mouse) | 325 aa |
Protein Details: Q9JII6 (Akr1a1)
Protein Information
| Accession | Q9JII6 |
|---|---|
| Protein Names | Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) (S-nitroso-CoA reductase) (ScorR) (EC 1.6.-.-) |
| Gene Symbol | Akr1a1 |
| Organism | Mus musculus (Mouse) |
| Length | 325 aa |
| Isoforms | No isoforms |
| Related PMIDs | 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTASSVLLHT11GQKMPLIGLG21TWKSEPGQVK31AAIKHALSAG41YRHIDCASVY
51-10051GNETEIGEAL61KESVGSGKAV71PREELFVTSK81LWNTKHHPED91VEPALRKTLA
101-150101DLQLEYLDLY111LMHWPYAFER121GDNPFPKNAD131GTVRYDSTHY141KETWKALEVL
151-200151VAKGLVKALG161LSNFNSRQID171DVLSVASVRP181AVLQVECHPY191LAQNELIAHC
201-250201HARGLEVTAY211SPLGSSDRAW221RHPDEPVLLE231EPVVLALAEK241HGRSPAQILL
251-300251RWQVQRKVIC261IPKSINPSRI271LQNIQVFDFT281FSPEEMKQLD291ALNKNWRYIV
301-325301PMITVDGKRV311PRDAGHPLYP321FNDPY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 46 | SWISSPALM DBPTM CYSMODDB | NADP-dependent oxidoreductase domain superfamily Aldo-keto reductase Aldo/keto reductase family | - |
Brain
(35358180)
|
Deep-Palm: 0.87
|
| 187 | - | - | - |
Deep-Palm: 0.59
|
|
| 200 | - | - | - |
Deep-Palm: 0.85
|
|
| 260 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.154
4/4 (100.0%)
1
Brain
Specificity: 0.038
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
21
Brain tissue (Mass)
Specificity: 0.808
21/56 (37.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.