Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9JJZ2 Tuba8 Tubulin alpha-8 chain (EC 3.6.5.-) … Mus musculus (Mouse) 449 aa

Protein Details: Q9JJZ2 (Tuba8)

Protein Information
AccessionQ9JJZ2
Protein NamesTubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene SymbolTuba8
OrganismMus musculus (Mouse)
Length449 aa
IsoformsNo isoforms
Related PMIDs 28526873 29660268 29733200 34200797 34884899 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRECISVHVG11QAGVQIGNAC21WELFCLEHGI31QADGTFGTQA41SKINDDDSFT
51-10051TFFSETGNGK61HVPRAVMVDL71EPTVVDEVRA81GTYRQLFHPE91QLITGKEDAA
101-150101NNYARGHYTV111GKESIDLVLD121RIRKLTDACS131GLQGFLIFHS141FGGGTGSGFT
151-200151SLLMERLSLD161YGKKSKLEFA171IYPAPQVSTA181VVEPYNSILT191THTTLEHSDC
201-250201AFMVDNEAIY211DICRRNLDIE221RPTYTNLNRL231ISQIVSSITA241SLRFDGALNV
251-300251DLTEFQTNLV261PYPRIHFPLV271TYAPIISAEK281AYHEQLSVAE291ITSSCFEPNS
301-350301QMVKCDPRHG311KYMACCMLYR321GDVVPKDVNV331AIAAIKTKRT341IQFVDWCPTG
351-400351FKVGINYQPP361TVVPGGDLAK371VQRAVCMLSN381TTAIAEAWAR391LDHKFDLMYA
401-449401KRAFVHWYVG411EGMEEGEFSE421AREDLAALEK431DYEEVGTDSF441EEENEGEEF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 Tubulin/FtsZ, GTPase domain superfamily - -
GPS-Palm: 0.94
Deep-Palm: 0.02
20 Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily - -
Deep-Palm: 0.58
25 Tubulin/FtsZ, GTPase domain superfamily Tubulin/FtsZ, GTPase domain Alpha tubulin - -
Deep-Palm: 0.33
129 - - -
Deep-Palm: 0.65
200 - - -
Deep-Palm: 0.07
213 - - -
Deep-Palm: 0.16
295 - - -
Deep-Palm: 0.18
305 - - -
Deep-Palm: 0.05
315 - - -
Deep-Palm: 0.19
316 - - -
GPS-Palm: 0.91
Deep-Palm: 0.33
347 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.37
376 - -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Brain
Specificity: 0.139
5/5 (100.0%)
2
Liver
Specificity: 0.056
2/2 (100.0%)
2
Testis
Specificity: 0.056
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
27
Brain tissue (Mass)
Specificity: 0.750
27/56 (48.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine