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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9NRX5 SERINC1; KIAA1253; TDE1L; TDE2; UNQ396/PRO732 Serine incorporator 1 (Tumor differentially … Homo sapiens (Human) 453 aa

Protein Details: Q9NRX5 (SERINC1)

Protein Information
Accession Q9NRX5
Protein Names Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2)
Gene Symbol SERINC1; KIAA1253; TDE1L; TDE2; UNQ396/PRO732
Organism Homo sapiens (Human)
Length 453 aa
Isoforms No isoforms
Related PMIDs 19801377 24357059 26111759 29575903 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.596
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
28
LNCaP cells
Specificity: 0.596
28/46 (60.9%)
4
PC3 cells
Specificity: 0.085
4/4 (100.0%)
4
T cells
Specificity: 0.085
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.085
4/4 (100.0%)
3
Jurkat T cells
Specificity: 0.064
3/25 (12.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
HeLa cells
Specificity: 0.021
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.021
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGSVLGLCSM11ASWIPCLCGS21APCLLCRCCP31SGNNSTVTRL41IYALFLLVGV
51-10051CVACVMLIPG61MEEQLNKIPG71FCENEKGVVP81CNILVGYKAV91YRLCFGLAMF
101-150101YLLLSLLMIK111VKSSSDPRAA121VHNGFWFFKF131AAAIAIIIGA141FFIPEGTFTT
151-200151VWFYVGMAGA161FCFILIQLVL171LIDFAHSWNE181SWVEKMEEGN191SRCWYAALLS
201-250201ATALNYLLSL211VAIVLFFVYY221THPASCSENK231AFISVNMLLC241VGASVMSILP
251-300251KIQESQPRSG261LLQSSVITVY271TMYLTWSAMT281NEPETNCNPS291LLSIIGYNTT
301-350301STVPKEGQSV311QWWHAQGIIG321LILFLLCVFY331SSIRTSNNSQ341VNKLTLTSDE
351-400351STLIEDGGAR361SDGSLEDGDD371VHRAVDNERD381GVTYSYSFFH391FMLFLASLYI
401-450401MMTLTNWYRY411EPSREMKSQW421TAVWVKISSS431WIGIVLYVWT441LVAPLVLTNR
451-453451DFD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
8 Prediction (Low) - -
23 Prediction (Medium) - -
26 Prediction (Medium) - -
29 Prediction (Medium) - -
81 CYSMODDB SWISSPALM DBPTM Serine incorporator (Serinc) -
94 Prediction (Low) - -
240 Prediction (Low) - -
327 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
26 C → Y 0.002288 SNP Missense Mutation STAD
152 W → C 0.001014 SNP Missense Mutation BRCA
217 F → C 0.002506 SNP Missense Mutation COAD
220 Y → C 0.001887 SNP Missense Mutation UCEC
385 S → C 0.002545 SNP Missense Mutation GBM
408 Y → C 0.001887 SNP Missense Mutation UCEC
410 Y → C 0.001969 SNP Missense Mutation HNSC
424 W → C 0.002033 SNP Missense Mutation LUSC
431 W → C 0.003559 SNP Missense Mutation KIRP
450 R → C 0.007299 SNP Missense Mutation READ