Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NRY6 | PLSCR3 | Phospholipid scramblase 3 (PL scramblase … | Homo sapiens (Human) | 295 aa |
Protein Details: Q9NRY6 (PLSCR3)
Protein Information
| Accession | Q9NRY6 |
|---|---|
| Protein Names | Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3) |
| Gene Symbol | PLSCR3 |
| Organism | Homo sapiens (Human) |
| Length | 295 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 22496122 24357059 26111759 29733200 31251020 31382980 32651440 32944167 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGYLPPKGY11APSPPPPYPV21TPGYPEPALH31PGPGQAPVPA41QVPAPAPGFA
51-10051LFPSPGPVAL61GSAAPFLPLP71GVPSGLEFLV81QIDQILIHQK91AERVETFLGW
101-150101ETCNRYELRS111GAGQPLGQAA121EESNCCARLC131CGARRPLRVR141LADPGDREVL
151-200151RLLRPLHCGC161SCCPCGLQEM171EVQAPPGTTI181GHVLQTWHPF191LPKFSIQDAD
201-250201RQTVLRVVGP211CWTCGCGTDT221NFEVKTRDES231RSVGRISKQW241GGLVREALTD
251-295251ADDFGLQFPL261DLDVRVKAVL271LGATFLIDYM281FFEKRGGAGP291SAVTS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 103 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.98
|
|
| 125 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.93
|
| 126 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.94
Deep-Palm: 0.94
|
| 130 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
|
| 131 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.95
|
|
| 158 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 160 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 162 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.96
|
|
| 163 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.94
|
|
| 165 | - | - | - |
Deep-Palm: 0.84
|
|
| 211 | DBPTM SWISSPALM | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.69
Deep-Palm: 0.84
|
| 214 | DBPTM SWISSPALM | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.55
|
| 216 | DBPTM SWISSPALM | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.79
Deep-Palm: 0.55
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.261
6
Jurkat T cell
Specificity: 0.222
6/6 (100.0%)
4
Primary T cell
Specificity: 0.148
4/4 (100.0%)
4
PC3
Specificity: 0.148
4/4 (100.0%)
3
LNCaP
Specificity: 0.111
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.037
1/1 (100.0%)
1
U937 cell
Specificity: 0.037
1/1 (100.0%)
1
EC cell
Specificity: 0.037
1/1 (100.0%)
1
heart
Specificity: 0.037
1/1 (100.0%)
1
HUVECs
Specificity: 0.037
1/1 (100.0%)
1
DU145 cell
Specificity: 0.037
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP cells (Mass)
Specificity: 0.074
2/4 (50.0%)
2
Cerebral Cortex (Mass)
Specificity: 0.074
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.