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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9NRZ7-2 AGPAT3 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) … Homo sapiens (Human) 314 aa

Protein Details: Q9NRZ7-2 (AGPAT3)

Protein Information
AccessionQ9NRZ7-2
Protein Names1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma)
Gene SymbolAGPAT3
OrganismHomo sapiens (Human)
Length314 aa
Isoforms
Related PMIDs 31251020
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLLEWWSCTE11CTLFTDQATV21ERFGKEHAVI31ILNHNFEIDF41LCGWTMCERF
51-10051GVLGSSKVLA61KKELLYVPLI71GWTWYFLEIV81FCKRKWEEDR91DTVVEGLRRL
101-150101SDYPEYMWFL111LYCEGTRFTE121TKHRVSMEVA131AAKGLPVLKY141HLLPRTKGFT
151-200151TAVKCLRGTV161AAVYDVTLNF171RGNKNPSLLG181ILYGKKYEAD191MCVRRFPLED
201-250201IPLDEKEAAQ211WLHKLYQEKD221ALQEIYNQKG231MFPGEQFKPA241RRPWTLLNFL
251-300251SWATILLSPL261FSFVLGVFAS271GSPLLILTFL281GFVGAASFGV291RRLIGVTEIE
301-314301KGSSYGNQEF311KKKE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
34 - - -
Deep-Palm: 0.92
51 - - -
Deep-Palm: 0.94
70 - - -
Deep-Palm: 0.18
73 - - -
Deep-Palm: 0.27
104 - - -
Deep-Palm: 0.54
109 - - -
Deep-Palm: 0.80
144 - - -
Deep-Palm: 0.70
155 - - -
GPS-Palm: 0.91
175 - - -
Deep-Palm: 0.49
217 - - -
Deep-Palm: 0.97
254 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
254 C → C 0.002294 SNP Silent OV
306 W → C 0.002545 SNP Missense Mutation GBM
314 W → C 0.002506 SNP Missense Mutation COAD
353 R → C 0.002506 SNP Missense Mutation COAD
353 R → C 0.007299 SNP Missense Mutation READ
353 R → C 0.002141 SNP Missense Mutation SKCM
353 R → C 0.003774 SNP Missense Mutation UCEC
353 R → C 0.005618 SNP Missense Mutation PAAD