Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NUQ2 | AGPAT5 | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) … | Homo sapiens (Human) | 364 aa |
Protein Details: Q9NUQ2 (AGPAT5)
Protein Information
| Accession | Q9NUQ2 |
|---|---|
| Protein Names | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon) |
| Gene Symbol | AGPAT5 |
| Organism | Homo sapiens (Human) |
| Length | 364 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLLSLVLHTY11SMRYLLPSVV21LLGTAPTYVL31AWGVWRLLSA41FLPARFYQAL
51-10051DDRLYCVYQS61MVLFFFENYT71GVQILLYGDL81PKNKENIIYL91ANHQSTVDWI
101-150101VADILAIRQN111ALGHVRYVLK121EGLKWLPLYG131CYFAQHGGIY141VKRSAKFNEK
151-200151EMRNKLQSYV161DAGTPMYLVI171FPEGTRYNPE181QTKVLSASQA191FAAQRGLAVL
201-250201KHVLTPRIKA211THVAFDCMKN221YLDAIYDVTV231VYEGKDDGGQ241RRESPTMTEF
251-300251LCKECPKIHI261HIDRIDKKDV271PEEQEHMRRW281LHERFEIKDK291MLIEFYESPD
301-350301PERRKRFPGK311SVNSKLSIKK321TLPSMLILSG331LTAGMLMTDA341GRKLYVNTWI
351-364351YGTLLGCLWV361TIKA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 56 | - | - | - |
Deep-Palm: 0.30
|
|
| 131 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.97
|
|
| 217 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.12
|
|
| 252 | - | - | - |
Deep-Palm: 0.46
|
|
| 255 | - | - | - |
Deep-Palm: 0.22
|
|
| 357 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
Primary T cell
Specificity: 0.600
3/3 (100.0%)
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 116 | R → C | 0.002288 | SNP | Missense Mutation | STAD |