Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9NVE7 PANK4 4'-phosphopantetheine phosphatase (EC 3.1.3.-) (Inactive … Homo sapiens (Human) 773 aa

Protein Details: Q9NVE7 (PANK4)

Protein Information
Accession Q9NVE7
Protein Names 4'-phosphopantetheine phosphatase (EC 3.1.3.-) (Inactive pantothenic acid kinase 4) (hPanK4)
Gene Symbol PANK4
Organism Homo sapiens (Human)
Length 773 aa
Isoforms No isoforms
Related PMIDs 24357059
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Endothelial cells
Specificity: 1.000
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAECGASGSG11SSGDSLDKSI21TLPPDEIFRN31LENAKRFAID41IGGSLTKLAY
51-10051YSTVQHKVAK61VRSFDHSGKD71TEREHEPPYE81ISVQEEITAR91LHFIKFENTY
101-150101IEACLDFIKD111HLVNTETKVI121QATGGGAYKF131KDLIEEKLRL141KVDKEDVMTC
151-200151LIKGCNFVLK161NIPHEAFVYQ171KDSDPEFRFQ181TNHPHIFPYL191LVNIGSGVSI
201-250201VKVETEDRFE211WVGGSSIGGG221TFWGLGALLT231KTKKFDELLH241LASRGQHSNV
251-300251DMLVRDVYGG261AHQTLGLSGN271LIASSFGKSA281TADQEFSKED291MAKSLLHMIS
301-350301NDIGQLACLH311ARLHSLDRVY321FGGFFIRGHP331VTMRTITYSI341NFFSKGEVQA
351-400351LFLRHEGYLG361AIGAFLKGAE371QDNPNQYSWG381ENYAGSSGLM391SASPELGPAQ
401-450401RARSGTFDLL411EMDRLERPLV421DLPLLLDPPS431YVPDTVDLTD441DALARKYWLT
451-500451CFEEALDGVV461KRAVASQPDS471VDAAERAEKF481RQKYWNKLQT491LRQQPFAYGT
501-550501LTVRSLLDTR511EHCLNEFNFP521DPYSKVKQRE531NGVALRCFPG541VVRSLDALGW
551-600551EERQLALVKG561LLAGNVFDWG571AKAVSAVLES581DPYFGFEEAK591RKLQERPWLV
601-650601DSYSEWLQRL611KGPPHKCALI621FADNSGIDII631LGVFPFVREL641LLRGTEVILA
651-700651CNSGPALNDV661THSESLIVAE671RIAGMDPVVH681SALQEERLLL691VQTGSSSPCL
701-750701DLSRLDKGLA711ALVRERGADL721VVIEGMGRAV731HTNYHAALRC741ESLKLAVIKN
751-773751AWLAERLGGR761LFSVIFKYEV771PAE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
4 Prediction (High) - -
150 Prediction (Medium) - -
155 Prediction (Medium) - -
308 Prediction (Medium) - -
451 Prediction (Low) - -
537 Prediction (Low) - -
651 Prediction (Medium) - -
699 Prediction (High) - -
740 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
73 R → C 0.002506 SNP Missense Mutation COAD
106 D → _F107insSCLD 0.002747 INS In Frame Ins LIHC
504 R → C 0.002545 SNP Missense Mutation GBM
617 C → C 0.001887 SNP Silent UCEC
651 C → F 0.005435 SNP Missense Mutation ESCA
728 R → C 0.002506 SNP Missense Mutation COAD