Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NW21 | CYRIB; CYRI; FAM49B; BM-009 | CYFIP-related Rac1 interactor B (L1) | Homo sapiens (Human) | 324 aa |
Protein Details: Q9NW21 (CYRIB)
Protein Information
| Accession | Q9NW21 |
|---|---|
| Protein Names | CYFIP-related Rac1 interactor B (L1) |
| Gene Symbol | CYRIB; CYRI; FAM49B; BM-009 |
| Organism | Homo sapiens (Human) |
| Length | 324 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32651440 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNLLKVLTC11TDLEQGPNFF21LDFENAQPTE31SEKEIYNQVN41VVLKDAEGIL
51-10051EDLQSYRGAG61HEIREAIQHP71ADEKLQEKAW81GAVVPLVGKL91KKFYEFSQRL
101-150101EAALRGLLGA111LTSTPYSPTQ121HLEREQALAK131QFAEILHFTL141RFDELKMTNP
151-200151AIQNDFSYYR161RTLSRMRINN171VPAEGENEVN181NELANRMSLF191YAEATPMLKT
201-250201LSDATTKFVS211ENKNLPIENT221TDCLSTMASV231CRVMLETPEY241RSRFTNEETV
251-300251SFCLRVMVGV261IILYDHVHPV271GAFAKTSKID281MKGCIKVLKD291QPPNSVEGLL
301-324301NALRYTTKHL311NDETTSKQIK321SMLQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | - | - | - |
Deep-Palm: 0.03
|
|
| 223 | - | - | - |
Deep-Palm: 0.59
|
|
| 231 | - | - | - |
Deep-Palm: 0.21
|
|
| 253 | - | - | - |
Deep-Palm: 0.41
|
|
| 284 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP
Specificity: 0.500
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 159 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 253 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 284 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 253* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |