Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NWQ8 | PAG1; CBP; PAG | Phosphoprotein associated with glycosphingolipid-enriched microdomains … | Homo sapiens (Human) | 432 aa |
Protein Details: Q9NWQ8 (PAG1)
Protein Information
| Accession | Q9NWQ8 |
|---|---|
| Protein Names | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp) |
| Gene Symbol | PAG1; CBP; PAG |
| Organism | Homo sapiens (Human) |
| Length | 432 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 25914232 26111759 31251020 31382980 32651440 |
| Database Sources | dbPTM |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.600
24/46 (52.2%)
7
Jurkat T cells
Specificity: 0.175
7/25 (28.0%)
3
T cells
Specificity: 0.075
3/4 (75.0%)
3
CEMx174 cells
Specificity: 0.075
3/3 (100.0%)
2
DU145 cells
Specificity: 0.050
2/2 (100.0%)
1
U937 cells
Specificity: 0.025
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGPAGSLLGS11GQMQITLWGS21LAAVAIFFVI31TFLIFLCSSC41DREKKPRQHS
51-10051GDHENLMNVP61SDKEMFSRSV71TSLATDAPAS81SEQNGALTNG91DILSEDSTLT
101-150101CMQHYEEVQT111SASDLLDSQD121STGKPKCHQS131RELPRIPPES141AVDTMLTARS
151-200151VDGDQGLGME161GPYEVLKDSS171SQENMVEDCL181YETVKEIKEV191AAAAHLEKGH
201-250201SGKAKSTSAS211KELPGPQTEG221KAEFAEYASV231DRNKKCRQSV241NVESILGNSC
251-300251DPEEEAPPPV261PVKLLDENEN271LQEKEGGEAE281ESATDTTSET291NKRFSSLSYK
301-350301SREEDPTLTE311EEISAMYSSV321NKPGQLVNKS331GQSLTVPEST341YTSIQGDPQR
351-400351SPSSCNDLYA361TVKDFEKTPN371STLPPAGRPS381EEPEPDYEAI391QTLNREEEKA
401-432401TLGTNGHHGL411VPKENDYESI421SDLQQGRDIT431RL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 37 | DBPTM Prediction (High) | Phosphoprotein associated with glycosphingolipid-enriched | - |
| 40 | DBPTM Prediction (Medium) | Phosphoprotein associated with glycosphingolipid-enriched | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 179 | C → C | 0.001887 | SNP | Silent | UCEC |
| 237 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 341 | Y → C | 0.002294 | SNP | Missense Mutation | OV |