Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NWU1-2 | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) … | Homo sapiens (Human) | 376 aa |
Protein Details: Q9NWU1-2 (OXSM)
Protein Information
| Accession | Q9NWU1-2 |
|---|---|
| Protein Names | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase) |
| Gene Symbol | OXSM |
| Organism | Homo sapiens (Human) |
| Length | 376 aa |
| Isoforms | |
| Related PMIDs | 31251020 32651440 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSNCLQNFLK11ITSTRLLCSR21LCQQLRSKRK31FFGTVPISRL41HRRVVITGIG
51-10051LVTPLGVGTH61LVWDRLIGGE71SGIVSLVGEE81YKSIPCSVAA91YVPRGSDEGQ
101-150101FNEQNFVSKS111DIKSMSSPTI121MAIGAAELAM131KDSGWHPQSE141ADQVATGVAI
151-200151GMGMIPLEVV161SETALNFQTK171GYNKVSPFFV181PKILVNMAAG191QVSIRYKLKG
201-250201PNHAVSTACT211TGAHAVGDSF221RFIAHGDAGH231ITAPDPEGEG241ALRCMAAALK
251-300251DAGVQPEEIS261YINAHATSTP271LGDAAENKAI281KHLFKDHAYA291LAVSSTKGAT
301-350301GHLLGAAGAV311EAAFTTLACY321YQKLPPTLNL331DCSEPEFDLN341YVPLKAQEWK
351-376351TEKRFIGLTN361SFGFGGTNAT371LCIAGL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.03
|
|
| 18 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.93
|
|
| 22 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.93
|
|
| 86 | - | - | - |
Deep-Palm: 0.91
|
|
| 209 | - | - | - |
Deep-Palm: 0.93
|
|
| 239 | - | - | - |
Deep-Palm: 0.98
|
|
| 264 | - | - | - |
Deep-Palm: 0.92
|
|
| 327 | - | - | - |
Deep-Palm: 0.97
|
|
| 372 | - | - | - |
GPS-Palm: 0.94
|
|
| 402 | - | - | - |
Deep-Palm: 0.98
|
|
| 415 | - | - | - |
Deep-Palm: 0.84
|
|
| 455 | - | - | - |
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
2
PC3
Specificity: 0.250
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.250
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 65 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 65 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 65 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 180 | V → Cfs*3 | 0.002506 | INS | Frame Shift Ins | COAD |
| 200 | G → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 239 | C → F | 0.001969 | SNP | Missense Mutation | HNSC |
| 402 | C → S | 0.002747 | SNP | Missense Mutation | LIHC |
| 402 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |
| 438 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |