Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NX63 | CHCHD3; MIC19; MINOS3 | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix … | Homo sapiens (Human) | 227 aa |
Protein Details: Q9NX63 (CHCHD3)
Protein Information
| Accession | Q9NX63 |
|---|---|
| Protein Names | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) |
| Gene Symbol | CHCHD3; MIC19; MINOS3 |
| Organism | Homo sapiens (Human) |
| Length | 227 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.694
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.694
25/46 (54.3%)
10
HAP1 cells
Specificity: 0.278
10/10 (100.0%)
1
CEMx174 cells
Specificity: 0.028
1/3 (33.3%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGGTTSTRRV11TFEADENENI21TVVKGIRLSE31NVIDRMKESS41PSGSKSQRYS
51-10051GAYGASVSDE61ELKRRVAEEL71ALEQAKKESE81DQKRLKQAKE91LDRERAAANE
101-150101QLTRAILRER111ICSEEERAKA121KHLARQLEEK131DRVLKKQDAF141YKEQLARLEE
151-200151RSSEFYRVTT161EQYQKAAEEV171EAKFKRYESH181PVCADLQAKI191LQCYRENTHQ
201-227201TLKCSALATQ211YMHCVNHAKQ221SMLEKGG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 112 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 117 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 183 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 195 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 195 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 204* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |