Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NX63 | CHCHD3 | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix … | Homo sapiens (Human) | 227 aa |
Protein Details: Q9NX63 (CHCHD3)
Protein Information
| Accession | Q9NX63 |
|---|---|
| Protein Names | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) |
| Gene Symbol | CHCHD3 |
| Organism | Homo sapiens (Human) |
| Length | 227 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGGTTSTRRV11TFEADENENI21TVVKGIRLSE31NVIDRMKESS41PSGSKSQRYS
51-10051GAYGASVSDE61ELKRRVAEEL71ALEQAKKESE81DQKRLKQAKE91LDRERAAANE
101-150101QLTRAILRER111ICSEEERAKA121KHLARQLEEK131DRVLKKQDAF141YKEQLARLEE
151-200151RSSEFYRVTT161EQYQKAAEEV171EAKFKRYESH181PVCADLQAKI191LQCYRENTHQ
201-227201TLKCSALATQ211YMHCVNHAKQ221SMLEKGG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 112 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.96
|
|
| 183 | - | - | - |
Deep-Palm: 0.88
|
|
| 193 | - | - | - |
Deep-Palm: 0.87
|
|
| 204 | - | - | - |
Deep-Palm: 0.22
|
|
| 214 | - | - | - |
Deep-Palm: 0.51
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.400
2/2 (100.0%)
1
CEM 174 cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 117 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 183 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 195 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 195 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 204* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |