Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NXU5 | ARL15 | ADP-ribosylation factor-like protein 15 (ADP-ribosylation … | Homo sapiens (Human) | 204 aa |
Protein Details: Q9NXU5 (ARL15)
Protein Information
| Accession | Q9NXU5 |
|---|---|
| Protein Names | ADP-ribosylation factor-like protein 15 (ADP-ribosylation factor-related protein 2) (ARF-related protein 2) |
| Gene Symbol | ARL15 |
| Organism | Homo sapiens (Human) |
| Length | 204 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 26111759 31251020 32651440 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSDLRITEAF11LYMDYLCFRA21LCCKGPPPAR31PEYDLVCIGL41TGSGKTSLLS
51-10051KLCSESPDNV61VSTTGFSIKA71VPFQNAILNV81KELGGADNIR91KYWSRYYQGS
101-150101QGVIFVLDSA111SSEDDLEAAR121NELHSALQHP131QLCTLPFLIL141ANHQDKPAAR
151-200151SVQEIKKYFE161LEPLARGKRW171ILQPCSLDDM181DALKDSFSQL191INLLEEKDHE
201-204201AVRM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | ADP-ribosylation factor-like protein 15 | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.92
|
|
| 22 | ADP-ribosylation factor-like protein 15 | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.60
|
|
| 23 | ADP-ribosylation factor-like protein 15 | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.73
|
|
| 37 | P-loop containing nucleoside triphosphate hydrolase ADP-ribosylation factor-like protein 15 | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.72
Deep-Palm: 0.98
|
|
| 53 | SWISSPALM DBPTM CYSMODDB | ADP-ribosylation factor family | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.78
Deep-Palm: 0.98
|
| 133 | - | - | - |
Deep-Palm: 0.97
|
|
| 175 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.353
6
Jurkat T cell
Specificity: 0.286
6/6 (100.0%)
3
LNCaP
Specificity: 0.143
3/3 (100.0%)
3
Primary T cell
Specificity: 0.143
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.143
3/3 (100.0%)
1
heart
Specificity: 0.048
1/1 (100.0%)
1
HUVECs
Specificity: 0.048
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Cerebral Cortex (Mass)
Specificity: 0.143
3/4 (75.0%)
1
LNCaP cells (Mass)
Specificity: 0.048
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 37 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 53 | C → Sfs*26 | 0.006993 | DEL | Frame Shift Del | LAML |
| 95 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 133 | C → Y | 0.005435 | SNP | Missense Mutation | ESCA |