Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NZ45 | CISD1; C10orf70; ZCD1; MDS029 | CDGSH iron-sulfur domain-containing protein 1 … | Homo sapiens (Human) | 108 aa |
Protein Details: Q9NZ45 (CISD1)
Protein Information
| Accession | Q9NZ45 |
|---|---|
| Protein Names | CDGSH iron-sulfur domain-containing protein 1 (Cysteine transaminase CISD1) (EC 2.6.1.3) (MitoNEET) |
| Gene Symbol | CISD1; C10orf70; ZCD1; MDS029 |
| Organism | Homo sapiens (Human) |
| Length | 108 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 32944167 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.667
24/46 (52.2%)
4
HAP1 cells
Specificity: 0.111
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.111
4/4 (100.0%)
2
PC3 cells
Specificity: 0.056
2/4 (50.0%)
1
Endothelial cells
Specificity: 0.028
1/2 (50.0%)
1
Liver membrane
Specificity: 0.028
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSLTSSSSVR11VEWIAAVTIA21AGTAAIGYLA31YKRFYVKDHR41NKAMINLHIQ
51-10051KDNPKIVHAF61DMEDLGDKAV71YCRCWRSKKF81PFCDGAHTKH91NEETGDNVGP
101-108101LIIKKKET
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 72 | Prediction (Medium) | - | - |
| 74 | Prediction (Medium) | - | - |
| 83 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 73 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |