Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NZQ7 | CD274 | Programmed cell death 1 ligand … | Homo sapiens (Human) | 290 aa |
Protein Details: Q9NZQ7 (CD274)
Protein Information
| Accession | Q9NZQ7 |
|---|---|
| Protein Names | Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274) |
| Gene Symbol | CD274 |
| Organism | Homo sapiens (Human) |
| Length | 290 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRIFAVFIFM11TYWHLLNAFT21VTVPKDLYVV31EYGSNMTIEC41KFPVEKQLDL
51-10051AALIVYWEME61DKNIIQFVHG71EEDLKVQHSS81YRQRARLLKD91QLSLGNAALQ
101-150101ITDVKLQDAG111VYRCMISYGG121ADYKRITVKV131NAPYNKINQR141ILVVDPVTSE
151-200151HELTCQAEGY161PKAEVIWTSS171DHQVLSGKTT181TTNSKREEKL191FNVTSTLRIN
201-250201TTTNEIFYCT211FRRLDPEENH221TAELVIPELP231LAHPPNERTH241LVILGAILLC
251-290251LGVALTFIFR261LRKGRMMDVK271KCGIQDTNSK281KQSDTHLEET
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 40 | Immunoglobulin-like fold | - | - |
Deep-Palm: 0.72
|
|
| 114 | - | - | - |
Deep-Palm: 0.45
|
|
| 155 | - | - | - |
Deep-Palm: 0.57
|
|
| 209 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.30
|
|
| 250 | - | - | - |
Deep-Palm: 0.98
|
|
| 272 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.72
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 57 | W → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 167 | W → C | 0.003460 | SNP | Missense Mutation | CESC |
| 260 | R → C | 0.002506 | SNP | Missense Mutation | COAD |