Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9NZV1 | CRIM1; S52; UNQ1886/PRO4330 | Cysteine-rich motor neuron 1 protein … | Homo sapiens (Human) | 1036 aa |
Protein Details: Q9NZV1 (CRIM1)
Protein Information
| Accession | Q9NZV1 |
|---|---|
| Protein Names | Cysteine-rich motor neuron 1 protein (CRIM-1) (Cysteine-rich repeat-containing protein S52) [Cleaved into: Processed cysteine-rich motor neuron 1 protein] |
| Gene Symbol | CRIM1; S52; UNQ1886/PRO4330 |
| Organism | Homo sapiens (Human) |
| Length | 1036 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 37611173 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
1
Endothelial cells
Specificity: 1.000
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MYLVAGDRGL11AGCGHLLVSL21LGLLLLLARS31GTRALVCLPC41DESKCEEPRN
51-10051CPGSIVQGVC61GCCYTCASQR71NESCGGTFGI81YGTCDRGLRC91VIRPPLNGDS
101-150101LTEYEAGVCE111DENWTDDQLL121GFKPCNENLI131AGCNIINGKC141ECNTIRTCSN
151-200151PFEFPSQDMC161LSALKRIEEE171KPDCSKARCE181VQFSPRCPED191SVLIEGYAPP
201-250201GECCPLPSRC211VCNPAGCLRK221VCQPGNLNIL231VSKASGKPGE241CCDLYECKPV
251-300251FGVDCRTVEC261PPVQQTACPP271DSYETQVRLT281ADGCCTLPTR291CECLSGLCGF
301-350301PVCEVGSTPR311IVSRGDGTPG321KCCDVFECVN331DTKPACVFNN341VEYYDGDMFR
351-400351MDNCRFCRCQ361GGVAICFTAQ371CGEINCERYY381VPEGECCPVC391EDPVYPFNNP
401-450401AGCYANGLIL411AHGDRWREDD421CTFCQCVNGE431RHCVATVCGQ441TCTNPVKVPG
451-500451ECCPVCEEPT461IITVDPPACG471ELSNCTLTGK481DCINGFKRDH491NGCRTCQCIN
501-550501TEELCSERKQ511GCTLNCPFGF521LTDAQNCEIC531ECRPRPKKCR541PIICDKYCPL
551-600551GLLKNKHGCD561ICRCKKCPEL571SCSKICPLGF581QQDSHGCLIC591KCREASASAG
601-650601PPILSGTCLT611VDGHHHKNEE621SWHDGCRECY631CLNGREMCAL641ITCPVPACGN
651-700651PTIHPGQCCP661SCADDFVVQK671PELSTPSICH681APGGEYFVEG691ETWNIDSCTQ
701-750701CTCHSGRVLC711ETEVCPPLLC721QNPSRTQDSC731CPQCTDQPFR741PSLSRNNSVP
751-800751NYCKNDEGDI761FLAAESWKPD771VCTSCICIDS781VISCFSESCP791SVSCERPVLR
801-850801KGQCCPYCIE811DTIPKKVVCH821FSGKAYADEE831RWDLDSCTHC841YCLQGQTLCS
851-900851TVSCPPLPCV861EPINVEGSCC871PMCPEMYVPE881PTNIPIEKTN891HRGEVDLEVP
901-950901LWPTPSENDI911VHLPRDMGHL921QVDYRDNRLH931PSEDSSLDSI941ASVVVPIIIC
951-1000951LSIIIAFLFI961NQKKQWIPLL971CWYRTPTKPS981SLNNQLVSVD991CKKGTRVQVD
1001-10361001SSQRMLRIAE1011PDARFSGFYS1021MQKQNHLQAD1031NFYQTV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 13 | Prediction (Low) | - | - |
| 37 | Prediction (Medium) | - | - |
| 40 | Prediction (Medium) | - | - |
| 62 | Prediction (Low) | - | - |
| 63 | Prediction (Low) | - | - |
| 84 | Prediction (High) | - | - |
| 90 | Prediction (Low) | - | - |
| 160 | Prediction (Medium) | - | - |
| 174 | Prediction (Low) | - | - |
| 212 | Prediction (High) | - | - |
| 217 | Prediction (High) | - | - |
| 222 | Prediction (Low) | - | - |
| 284 | Prediction (Medium) | - | - |
| 285 | Prediction (Medium) | - | - |
| 293 | Prediction (Low) | - | - |
| 298 | Prediction (Low) | - | - |
| 303 | Prediction (Low) | - | - |
| 357 | Prediction (Low) | - | - |
| 366 | Prediction (Low) | - | - |
| 530 | Prediction (Low) | - | - |
| 532 | Prediction (Low) | - | - |
| 539 | Prediction (Low) | - | - |
| 544 | Prediction (Low) | - | - |
| 548 | Prediction (Medium) | - | - |
| 559 | Prediction (Medium) | - | - |
| 562 | Prediction (Medium) | - | - |
| 572 | Prediction (Low) | - | - |
| 772 | Prediction (Low) | - | - |
| 804 | Prediction (Medium) | - | - |
| 805 | Prediction (Medium) | - | - |
| 808 | Prediction (High) | - | - |
| 819 | Prediction (Medium) | - | - |
| 950 | Prediction (Low) | - | - |
| 971 | Experimental Prediction (Medium) | Cysteine-rich motor neuron 1 protein C-terminal | 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 37 | C → G | 0.010870 | SNP | Missense Mutation | ACC |
| 45 | C → C | 0.002033 | SNP | Silent | LUSC |
| 60 | C → C | 0.002427 | SNP | Silent | BLCA |
| 84 | C → S | 0.002427 | SNP | Missense Mutation | BLCA |
| 88 | L → Cfs*48 | 0.003774 | DEL | Frame Shift Del | UCEC |
| 109 | C → C | 0.001887 | SNP | Silent | UCEC |
| 174 | C → Lfs*7 | 0.001764 | INS | Frame Shift Ins | LUAD |
| 179 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 210 | C → C | 0.001887 | SNP | Silent | UCEC |
| 219 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 291 | C → C | 0.002506 | SNP | Silent | COAD |
| 313 | S → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 314 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 323 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 336 | C → C | 0.002506 | SNP | Silent | COAD |
| 354 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 373 | E → _I374insAAQCGE | 0.012195 | INS | In Frame Ins | MESO |
| 376 | C → C | 0.005618 | SNP | Silent | PAAD |
| 424 | C → C | 0.002294 | SNP | Silent | OV |
| 433 | C → C | 0.002506 | SNP | Silent | COAD |
| 433 | C → C | 0.001887 | SNP | Silent | UCEC |
| 481 | D → _C482del | 0.002033 | DEL | In Frame Del | LUSC |
| 482 | C → C | 0.001887 | SNP | Silent | UCEC |
| 508 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 532 | C → F | 0.001014 | SNP | Missense Mutation | BRCA |
| 544 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 548 | C → F | 0.002141 | SNP | Missense Mutation | SKCM |
| 563 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 629 | C → C | 0.010870 | SNP | Silent | ACC |
| 669 | Q → Cfs*114 | 0.004219 | INS | Frame Shift Ins | SARC |
| 701 | C → C | 0.002294 | SNP | Silent | OV |
| 794 | C → Lfs*6 | 0.002288 | DEL | Frame Shift Del | STAD |
| 837 | C → C | 0.001887 | SNP | Silent | UCEC |
| 548* | C → ? | 0.001764 | SNP | Nonsense Mutation | LUAD |
| 336* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |