Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9P0L9 PKD2L1 Polycystin-2-like protein 1 (Polycystin-2L1) (Polycystic … Homo sapiens (Human) 805 aa

Protein Details: Q9P0L9 (PKD2L1)

Protein Information
AccessionQ9P0L9
Protein NamesPolycystin-2-like protein 1 (Polycystin-2L1) (Polycystic kidney disease 2-like 1 protein) (Polycystin-2 homolog) (Polycystin-L) (Polycystin-L1)
Gene SymbolPKD2L1
OrganismHomo sapiens (Human)
Length805 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNAVGSPEGQ11ELQKLGSGAW21DNPAYSGPPS31PHGTLRVCTI41SSTGPLQPQP
51-10051KKPEDEPQET61AYRTQVSSCC71LHICQGIRGL81WGTTLTENTA91ENRELYIKTT
101-150101LRELLVYIVF111LVDICLLTYG121MTSSSAYYYT131KVMSELFLHT141PSDTGVSFQA
151-200151ISSMADFWDF161AQGPLLDSLY171WTKWYNNQSL181GHGSHSFIYY191ENMLLGVPRL
201-250201RQLKVRNDSC211VVHEDFREDI221LSCYDVYSPD231KEEQLPFGPF241NGTAWTYHSQ
251-300251DELGGFSHWG261RLTSYSGGGY271YLDLPGSRQG281SAEALRALQE291GLWLDRGTRV
301-350301VFIDFSVYNA311NINLFCVLRL321VVEFPATGGA331IPSWQIRTVK341LIRYVSNWDF
351-400351FIVGCEVIFC361VFIFYYVVEE371ILELHIHRLR381YLSSIWNILD391LVVILLSIVA
401-450401VGFHIFRTLE411VNRLMGKLLQ421QPNTYADFEF431LAFWQTQYNN441MNAVNLFFAW
451-500451IKIFKYISFN461KTMTQLSSTL471ARCAKDILGF481AVMFFIVFFA491YAQLGYLLFG
501-550501TQVENFSTFI511KCIFTQFRII521LGDFDYNAID531NANRILGPAY541FVTYVFFVFF
551-600551VLLNMFLAII561NDTYSEVKEE571LAGQKDELQL581SDLLKQGYNK591TLLRLRLRKE
601-650601RVSDVQKVLQ611GGEQEIQFED621FTNTLRELGH631AEHEITELTA641TFTKFDRDGN
651-700651RILDEKEQEK661MRQDLEEERV671ALNTEIEKLG681RSIVSSPQGK691SGPEAARAGG
701-750701WVSGEEFYML711TRRVLQLETV721LEGVVSQIDA731VGSKLKMLER741KGWLAPSPGV
751-800751KEQAIWKHPQ761PAPAVTPDPW771GVQGGQESEV781PYKREEEALE791ERRLSRGEIP
801-805801TLQRS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
38 DBPTM SWISSPALM - - -
Deep-Palm: 0.88
69 - - -
GPS-Palm: 0.82
Deep-Palm: 0.59
70 - - -
GPS-Palm: 0.89
Deep-Palm: 0.61
74 - - -
GPS-Palm: 0.83
Deep-Palm: 0.46
115 - - -
Deep-Palm: 0.39
210 - - -
GPS-Palm: 0.80
Deep-Palm: 0.96
223 - - -
Deep-Palm: 0.49
316 - - -
GPS-Palm: 0.72
Deep-Palm: 0.86
355 - - -
Deep-Palm: 0.03
360 - - -
Deep-Palm: 0.04
473 - - -
GPS-Palm: 0.78
Deep-Palm: 0.78
512 - - -
GPS-Palm: 0.78
Deep-Palm: 0.26
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
206 R → C 0.002545 SNP Missense Mutation GBM
242 G → C 0.001887 SNP Missense Mutation UCEC
245 W → C 0.002033 SNP Missense Mutation LUSC
360 C → F 0.001764 SNP Missense Mutation LUAD
438 Y → C 0.002141 SNP Missense Mutation SKCM
491 Y → C 0.002288 SNP Missense Mutation STAD
596 R → C 0.002020 SNP Missense Mutation PRAD
596 R → C 0.001887 SNP Missense Mutation UCEC
651 R → C 0.002141 SNP Missense Mutation SKCM
651 R → C 0.001887 SNP Missense Mutation UCEC