Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9P258 | RCC2; KIAA1470; TD60 | Protein RCC2 (RCC1-like protein TD-60) … | Homo sapiens (Human) | 522 aa |
Protein Details: Q9P258 (RCC2)
Protein Information
| Accession | Q9P258 |
|---|---|
| Protein Names | Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa) |
| Gene Symbol | RCC2; KIAA1470; TD60 |
| Organism | Homo sapiens (Human) |
| Length | 522 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.654
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.654
34/46 (73.9%)
10
HAP1 cells
Specificity: 0.192
10/10 (100.0%)
4
293T cells
Specificity: 0.077
4/10 (40.0%)
2
PC3 cells
Specificity: 0.038
2/4 (50.0%)
1
U937 cells
Specificity: 0.019
1/1 (100.0%)
1
HeLa cells
Specificity: 0.019
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPRKKAAAAA11WEEPSSGNGT21ARAGPRKRGG31PAGRKRERPE41RCSSSSGGGS
51-10051SGDEDGLELD61GAPGGGKRAA71RPATAGKAGG81AAVVITEPEH91TKERVKLEGS
101-150101KCKGQLLIFG111ATNWDLIGRK121EVPKQQAAYR131NLGQNLWGPH141RYGCLAGVRV
151-200151RTVVSGSCAA161HSLLITTEGK171LWSWGRNEKG181QLGHGDTKRV191EAPRLIEGLS
201-250201HEVIVSAACG211RNHTLALTET221GSVFAFGENK231MGQLGLGNQT241DAVPSPAQIM
251-300251YNGQPITKMA261CGAEFSMIMD271CKGNLYSFGC281PEYGQLGHNS291DGKFIARAQR
301-350301IEYDCELVPR311RVAIFIEKTK321DGQILPVPNV331VVRDVACGAN341HTLVLDSQKR
351-400351VFSWGFGGYG361RLGHAEQKDE371MVPRLVKLFD381FPGRGASQIY391AGYTCSFAVS
401-450401EVGGLFFWGA411TNTSRESTMY421PKAVQDLCGW431RIRSLACGKS441SIIVAADEST
451-500451ISWGPSPTFG461ELGYGDHKPK471SSTAAQEVKT481LDGIFSEQVA491MGYSHSLVIA
501-522501RDESETEKEK511IKKLPEYNPR521TL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 102 | Prediction (Low) | - | - |
| 144 | Prediction (Medium) | - | - |
| 158 | Prediction (Low) | - | - |
| 209 | Prediction (Medium) | - | - |
| 305 | Prediction (Low) | - | - |
| 337 | Prediction (Medium) | - | - |
| 428 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | 29575903 |
| 437 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 374 | R → C | 0.005013 | SNP | Missense Mutation | COAD |
| 384 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 384 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.001764 | SNP | Nonstop Mutation | LUAD |
| 428* | C → ? | 0.002294 | SNP | Nonsense Mutation | OV |