Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9P275 | USP36; KIAA1453 | Ubiquitin carboxyl-terminal hydrolase 36 (EC … | Homo sapiens (Human) | 1123 aa |
Protein Details: Q9P275 (USP36)
Protein Information
| Accession | Q9P275 |
|---|---|
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) |
| Gene Symbol | USP36; KIAA1453 |
| Organism | Homo sapiens (Human) |
| Length | 1123 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
8
LNCaP cells
Specificity: 0.800
8/46 (17.4%)
2
PC3 cells
Specificity: 0.200
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPIVDKLKEA11LKPGRKDSAD21DGELGKLLAS31SAKKVLLQKI41EFEPASKSFS
51-10051YQLEALKSKY61VLLNPKTEGA71SRHKSGDDPP81ARRQGSEHTY91ESCGDGVPAP
101-150101QKVLFPTERL111SLRWERVFRV121GAGLHNLGNT131CFLNATIQCL141TYTPPLANYL
151-200151LSKEHARSCH161QGSFCMLCVM171QNHIVQAFAN181SGNAIKPVSF191IRDLKKIARH
201-250201FRFGNQEDAH211EFLRYTIDAM221QKACLNGCAK231LDRQTQATTL241VHQIFGGYLR
251-300251SRVKCSVCKS261VSDTYDPYLD271VALEIRQAAN281IVRALELFVK291ADVLSGENAY
301-350301MCAKCKKKVP311ASKRFTIHRT321SNVLTLSLKR331FANFSGGKIT341KDVGYPEFLN
351-400351IRPYMSQNNG361DPVMYGLYAV371LVHSGYSCHA381GHYYCYVKAS391NGQWYQMNDS
401-450401LVHSSNVKVV411LNQQAYVLFY421LRIPGSKKSP431EGLISRTGSS441SLPGRPSVIP
451-500451DHSKKNIGNG461IISSPLTGKR471QDSGTMKKPH481TTEEIGVPIS491RNGSTLGLKS
501-550501QNGCIPPKLP511SGSPSPKLSQ521TPTHMPTILD531DPGKKVKKPA541PPQHFSPRTA
551-600551QGLPGTSNSN561SSRSGSQRQG571SWDSRDVVLS581TSPKLLATAT591ANGHGLKGND
601-650601ESAGLDRRGS611SSSSPEHSAS621SDSTKAPQTP631RSGAAHLCDS641QETNCSTAGH
651-700651SKTPPSGADS661KTVKLKSPVL671SNTTTEPAST681MSPPPAKKLA691LSAKKASTLW
701-750701RATGNDLRPP711PPSPSSDLTH721PMKTSHPVVA731STWPVHRARA741VSPAPQSSSR
751-800751LQPPFSPHPT761LLSSTPKPPG771TSEPRSCSSI781STALPQVNED791LVSLPHQLPE
801-850801ASEPPQSPSE811KRKKTFVGEP821QRLGSETRLP831QHIREATAAP841HGKRKRKKKK
851-900851RPEDTAASAL861QEGQTQRQPG871SPMYRREGQA881QLPAVRRQED891GTQPQVNGQQ
901-950901VGCVTDGHHA911SSRKRRRKGA921EGLGEEGGLH931QDPLRHSCSP941MGDGDPEAME
951-1000951ESPRKKKKKK961RKQETQRAVE971EDGHLKCPRS981AKPQDAVVPE991SSSCAPSANG
1001-10501001WCPGDRMGLS1011QAPPVSWNGE1021RESDVVQELL1031KYSSDKAYGR1041KVLTWDGKMS
1051-11001051AVSQDAIEDS1061RQARTETVVD1071DWDEEFDRGK1081EKKIKKFKRE1091KRRNFNAFQK
1101-11231101LQTRRNFWSV1111THPAKAASLS1121YRR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 224 | Prediction (High) | - | - |
| 228 | Prediction (High) | - | - |
| 255 | Prediction (Low) | - | - |
| 258 | Prediction (Low) | - | - |
| 302 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 305 | Prediction (Medium) | - | - |
| 504 | Prediction (Medium) | - | - |
| 777 | Prediction (Low) | - | - |
| 977 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 119 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 157 | R → C | 0.005587 | SNP | Missense Mutation | PCPG |
| 202 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 314 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 638 | C → C | 0.001887 | SNP | Silent | UCEC |
| 994 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 1006 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1122 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 1122 | R → C | 0.002294 | SNP | Missense Mutation | OV |