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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9P296 C5AR2 C5a anaphylatoxin chemotactic receptor 2 … Homo sapiens (Human) 337 aa

Protein Details: Q9P296 (C5AR2)

Protein Information
AccessionQ9P296
Protein NamesC5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene SymbolC5AR2
OrganismHomo sapiens (Human)
Length337 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNDSVSYEY11GDYSDLSDRP21VDCLDGACLA31IDPLRVAPLP41LYAAIFLVGV
51-10051PGNAMVAWVA61GKVARRRVGA71TWLLHLAVAD81LLCCLSLPIL91AVPIARGGHW
101-150101PYGAVGCRAL111PSIILLTMYA121SVLLLAALSA131DLCFLALGPA141WWSTVQRACG
151-200151VQVACGAAWT161LALLLTVPSA171IYRRLHQEHF181PARLQCVVDY191GGSSSTENAV
201-250201TAIRFLFGFL211GPLVAVASCH221SALLCWAARR231CRPLGTAIVV241GFFVCWAPYH
251-300251LLGLVLTVAA261PNSALLARAL271RAEPLIVGLA281LAHSCLNPML291FLYFGRAQLR
301-337301RSLPAACHWA311LRESQGQDES321VDSKKSTSHD331LVSEMEV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
23 - - -
Deep-Palm: 0.85
28 - - -
GPS-Palm: 0.70
Deep-Palm: 0.97
83 - - -
Deep-Palm: 0.94
84 - - -
GPS-Palm: 0.65
Deep-Palm: 0.93
107 - - -
GPS-Palm: 0.75
Deep-Palm: 0.84
133 - - -
GPS-Palm: 0.83
Deep-Palm: 0.98
149 - - -
Deep-Palm: 0.94
155 - - -
GPS-Palm: 0.75
Deep-Palm: 0.97
186 - - -
Deep-Palm: 0.68
219 - - -
Deep-Palm: 0.97
225 - - -
GPS-Palm: 0.83
Deep-Palm: 0.97
231 - - -
GPS-Palm: 0.77
Deep-Palm: 0.70
245 - - -
Deep-Palm: 0.67
285 - - -
Deep-Palm: 0.96
307 -
HeLa (37611173)
-
GPS-Palm: 0.93
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
23 C → C 0.005618 SNP Silent PAAD
28 C → C 0.001887 SNP Silent UCEC
35 R → C 0.002506 SNP Missense Mutation COAD
84 C → C 0.001014 SNP Silent BRCA
84 C → F 0.006993 SNP Missense Mutation LAML
96 R → C 0.005435 SNP Missense Mutation ESCA
149 C → S 0.002033 SNP Missense Mutation LUSC
159 W → C 0.002288 SNP Missense Mutation STAD
186 C → C 0.001887 SNP Silent UCEC
230 R → C 0.002288 SNP Missense Mutation STAD
309 W → C 0.002033 SNP Missense Mutation LUSC