Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9P2B2 | PTGFRN; CD9P1; EWIF; FPRP; KIAA1436 | Prostaglandin F2 receptor negative regulator … | Homo sapiens (Human) | 879 aa |
Protein Details: Q9P2B2 (PTGFRN)
Protein Information
| Accession | Q9P2B2 |
|---|---|
| Protein Names | Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) |
| Gene Symbol | PTGFRN; CD9P1; EWIF; FPRP; KIAA1436 |
| Organism | Homo sapiens (Human) |
| Length | 879 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 24357059 29575903 29733200 31251020 32944167 33636221 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.702
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
40
LNCaP cells
Specificity: 0.702
40/46 (87.0%)
4
PC3 cells
Specificity: 0.070
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.070
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.070
4/4 (100.0%)
2
DU145 cells
Specificity: 0.035
2/2 (100.0%)
1
HeLa cells
Specificity: 0.018
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGRLASRPLL11LALLSLALCR21GRVVRVPTAT31LVRVVGTELV41IPCNVSDYDG
51-10051PSEQNFDWSF61SSLGSSFVEL71ASTWEVGFPA81QLYQERLQRG91EILLRRTAND
101-150101AVELHIKNVQ111PSDQGHYKCS121TPSTDATVQG131NYEDTVQVKV141LADSLHVGPS
151-200151ARPPPSLSLR161EGEPFELRCT171AASASPLHTH181LALLWEVHRG191PARRSVLALT
201-250201HEGRFHPGLG211YEQRYHSGDV221RLDTVGSDAY231RLSVSRALSA241DQGSYRCIVS
251-300251EWIAEQGNWQ261EIQEKAVEVA271TVVIQPSVLR281AAVPKNVSVA291EGKELDLTCN
301-350301ITTDRADDVR311PEVTWSFSRM321PDSTLPGSRV331LARLDRDSLV341HSSPHVALSH
351-400351VDARSYHLLV361RDVSKENSGY371YYCHVSLWAP381GHNRSWHKVA391EAVSSPAGVG
401-450401VTWLEPDYQV411YLNASKVPGF421ADDPTELACR431VVDTKSGEAN441VRFTVSWYYR
451-500451MNRRSDNVVT461SELLAVMDGD471WTLKYGERSK481QRAQDGDFIF491SKEHTDTFNF
501-550501RIQRTTEEDR511GNYYCVVSAW521TKQRNNSWVK531SKDVFSKPVN541IFWALEDSVL
551-600551VVKARQPKPF561FAAGNTFEMT571CKVSSKNIKS581PRYSVLIMAE591KPVGDLSSPN
601-650601ETKYIISLDQ611DSVVKLENWT621DASRVDGVVL631EKVQEDEFRY641RMYQTQVSDA
651-700651GLYRCMVTAW661SPVRGSLWRE671AATSLSNPIE681IDFQTSGPIF691NASVHSDTPS
701-750701VIRGDLIKLF711CIITVEGAAL721DPDDMAFDVS731WFAVHSFGLD741KAPVLLSSLD
751-800751RKGIVTTSRR761DWKSDLSLER771VSVLEFLLQV781HGSEDQDFGN791YYCSVTPWVK
801-850801SPTGSWQKEA811EIHSKPVFIT821VKMDVLNAFK831YPLLIGVGLS841TVIGLLSCLI
851-879851GYCSSHWCCK861KEVQETRRER871RRLMSMEMD
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 19 | Prediction (High) | - | - |
| 169 | Prediction (Medium) | - | - |
| 299 | Prediction (Low) | - | - |
| 429 | Experimental Prediction (Low) | - | 29575903 |
| 571 | Prediction (Medium) | - | - |
| 655 | Prediction (Low) | - | - |
| 711 | Prediction (Medium) | - | - |
| 848 | Experimental CYSMODDB SWISSPALM DBPTM | - | 29575903 |
| 853 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 22 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 22 | R → C | 0.017544 | SNP | Missense Mutation | UCS |
| 119 | C → F | 0.002545 | SNP | Missense Mutation | GBM |
| 231 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 336 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 454 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 515 | C → S | 0.001969 | SNP | Missense Mutation | LGG |
| 582 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 788 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |