Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9QUR6 Prep Prolyl endopeptidase (PE) (EC 3.4.21.26) … Mus musculus (Mouse) 710 aa

Protein Details: Q9QUR6 (Prep)

Protein Information
AccessionQ9QUR6
Protein NamesProlyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)
Gene SymbolPrep
OrganismMus musculus (Mouse)
Length710 aa
IsoformsNo isoforms
Related PMIDs 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSFQYPDVY11RDETSVQEYH21GHKICDPYSW31LEDPDSEQTK41AFVEAQNKIT
51-10051VPFLEQCPIR61GLYKERMTEL71YDYPKYSCHF81KKGKRYFYFY91NTGLQNQRVL
101-150101YVQDSLEGEA111RVFLDPNTLS121DDGTVALRGY131AFSEDGEYFA141YGLSASGSDW
151-200151VTIKFMKVDG161AKELPDVLER171VKFTCMAWTH181DGKGMFYNSY191PQQDGKSDGT
201-250201ETSTNLHQKL211CYHVLGTDQS221EDILCAEFPD231EPKWMGGAEL241SDDGRYVLLS
251-300251IWEGCDPVNR261LWYCDLQQEP271NGITGILKWV281KLIDNFEGEY291DYVTNEGTVF
301-350301TFKTNRNSPN311YRLINIDFTD321PDESKWKVLV331PEHEKDVLEW341VACVRSNFLV
351-400351LCYLHDVKNI361LQLHDLTTGA371LLKTFPLDVG381SVVGYSGRKK391DSEIFYQFTS
401-450401FLSPGVIYHC411DLTKEELEPM421VFREVTVKGI431DAADYQTIQI441FYPSKDGTKI
451-500451PMFIVHKKGI461KLDGSHPAFL471YGYGGFNISI481TPNYSVSRLI491FVRHMGGVLA
501-550501VANIRGGGEY511GETWHKGGIL521ANKQNCFDDF531QCAAEYLIKE541GYTSPKRLTI
551-600551NGGSNGGLLV561AACANQRPDL571FGCVIAQVGV581MDMLKFHKFT591IGHAWTTDYG
601-650601CSDTKQHFEW611LLKYSPLHNV621KLPEADDIQY631PSMLLLTADH641DDRVVPLHSL
651-700651KFIATLQYIV661GRSRKQSNPL671LIHVDTKAGH681GAGKPTAKVI691EEVSDMFAFI
701-710701ARCLNIEWIQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
25 Peptidase S9A, N-terminal domain Alpha/Beta hydrolase fold Peptidase/esterase 'gauge' domain Prolyl oligopeptidase and macrocyclase - -
Deep-Palm: 0.52
57 -
brain (39008777)
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.86
78 - - -
Deep-Palm: 0.28
175 - - -
Deep-Palm: 0.78
211 SWISSPALM DBPTM CYSMODDB Prolyl oligopeptidase N-terminal beta-propeller domain
Forebrain (28680068)
-
Deep-Palm: 0.83
225 SWISSPALM DBPTM CYSMODDB Prolyl oligopeptidase N-terminal beta-propeller domain
Forebrain (28680068)
-
Deep-Palm: 0.75
255 - - -
Deep-Palm: 0.89
264 - - -
Deep-Palm: 0.20
343 - - -
Deep-Palm: 0.51
352 - -
Brain (35358180)
Deep-Palm: 0.75
410 - - -
Deep-Palm: 0.73
526 - - -
Deep-Palm: 0.14
532 - - -
Deep-Palm: 0.23
563 - - -
Deep-Palm: 0.93
573 - - -
Deep-Palm: 0.92
601 - - -
Deep-Palm: 0.08
703 - - -
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Liver
Specificity: 0.231
3/3 (100.0%)
1
Brain
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
9
Brain tissue (Mass)
Specificity: 0.692
9/56 (16.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine