Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9QYR9 Acot2 Acyl-coenzyme A thioesterase 2, mitochondrial … Mus musculus (Mouse) 453 aa

Protein Details: Q9QYR9 (Acot2)

Protein Information
AccessionQ9QYR9
Protein NamesAcyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase)
Gene SymbolAcot2
OrganismMus musculus (Mouse)
Length453 aa
IsoformsNo isoforms
Related PMIDs 34200797 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVASSFAVLR11ASRLCQQDWK21SWARLFVPPP31LSTGGRTTWA41RTNATLSVEP
51-10051EGRSCWDEPL61SIAVRGLAPE71QPVTLRSALR81DEKGALFRAH91ARYRADAGGE
101-150101LNLARAPALG111GSFSGLEPMG121LLWAMEPERP131LWRLIKRDVQ141TPFLVELEVL
151-200151DGHEPDGGQR161LAQAVHERHF171LAPGVRRVPV181REGRVRATLF191LPPEPGPFPG
201-250201IIDLFGVGGG211LLEYRASLLA221GKGFAVMALA231YYNYDDLPKS241IETMHMEYFE
251-300251EAVNYLRSHP261EVKGPGIGLL271GISKGGELGL281AMASFLKGIT291AAVVINGSVA
301-350301AVGNTISYKD311ETIPPVSLLR321NQVKMTKDGL331LDVVEALQSP341LVDKKSFIPV
351-400351ERSDTTFLFL361VGQDDHNWKS371EFYADEISKR381LQAHGKEKPQ391IICYPAAGHY
401-450401IEPPYFPLCS411AGMHLLVGAN421ITFGGEPRAH431AVAQVDAWQQ441LQTFFHKQLG
451-453451SKS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
15 - - -
GPS-Palm: 0.93
Deep-Palm: 0.82
55 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.96
393 - - -
Deep-Palm: 0.89
409 - - -
Deep-Palm: 0.78
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Liver
Specificity: 0.333
2/2 (100.0%)
1
Brain
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.500
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine