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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9R092 Hsd17b6 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD … Mus musculus (Mouse) 317 aa

Protein Details: Q9R092 (Hsd17b6)

Protein Information
AccessionQ9R092
Protein Names17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6) (17-beta-HSD6) (EC 1.1.1.105) (EC 1.1.1.209) (EC 1.1.1.239) (EC 1.1.1.53) (EC 1.1.1.62) (17-beta-HSD9) (3-alpha->beta-hydroxysteroid epimerase) (3-alpha->beta-HSE) (Oxidative 3-alpha hydroxysteroid dehydrogenase)
Gene SymbolHsd17b6
OrganismMus musculus (Mouse)
Length317 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MWFYLVTLVG11LYHLLRWYRE21RQVVSHLQDK31YVFITGCDSG41FGNLLARQLD
51-10051RRGMRVLAAC61LTEKGAEELR71NKTSDRLETV81ILDVTKTESI91VAATQWVKER
101-150101VGDRGLWGLV111NNAGVLQPFA121YIEWYRPEDY131MPIFQVNLIG141LTQVTISMLF
151-200151LVKKARGRIV161NVSSALGRVA171LFGGFYSCSK181YGVEAFSDVL191RHEVQDFGVK
201-250201VSIIEPGSFK211TEMTDAELTI221ERTKKVWEAA231PEHIKESYGQ241QFFDDFCSTT
251-300251KRELMKCSRN261LSLVTDCMEH271ALTSTHPRTR281YSAGWDAKFF291FIPLSYLPAS
301-317301LVDYLLAISR311GKPAQAA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
37 NAD(P)-binding domain superfamily SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C
Liver (28526873)
Liver (34884899)
GPS-Palm: 0.91
Deep-Palm: 0.95
60 -
Liver (28526873)
-
GPS-Palm: 0.95
Deep-Palm: 0.98
178 short chain dehydrogenase
Liver (28526873)
-
Deep-Palm: 0.97
247 DBPTM -
Liver (28526873)
-
Deep-Palm: 0.23
257 - - -
Deep-Palm: 0.52
267 -
Liver (28526873)
-
Deep-Palm: 0.75
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine