Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UBR2 | CTSZ | Cathepsin Z (EC 3.4.18.1) (Cathepsin … | Homo sapiens (Human) | 303 aa |
Protein Details: Q9UBR2 (CTSZ)
Protein Information
| Accession | Q9UBR2 |
|---|---|
| Protein Names | Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) |
| Gene Symbol | CTSZ |
| Organism | Homo sapiens (Human) |
| Length | 303 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 31251020 31382980 32944167 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MARRGPGWRP11LLLLVLLAGA21AQGGLYFRRG31QTCYRPLRGD41GLAPLGRSTY
51-10051PRPHEYLSPA61DLPKSWDWRN71VDGVNYASIT81RNQHIPQYCG91SCWAHASTSA
101-150101MADRINIKRK111GAWPSTLLSV121QNVIDCGNAG131SCEGGNDLSV141WDYAHQHGIP
151-200151DETCNNYQAK161DQECDKFNQC171GTCNEFKECH181AIRNYTLWRV191GDYGSLSGRE
201-250201KMMAEIYANG211PISCGIMATE221RLANYTGGIY231AEYQDTTYIN241HVVSVAGWGI
251-300251SDGTEYWIVR261NSWGEPWGER271GWLRIVTSTY281KDGKGARYNL291AIEEHCTFGD
301-303301PIV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 33 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.95
|
|
| 89 | - | - | - |
Deep-Palm: 0.04
|
|
| 92 | - | - | - |
Deep-Palm: 0.04
|
|
| 126 | - | - | - |
Deep-Palm: 0.75
|
|
| 132 | - | - | - |
Deep-Palm: 0.13
|
|
| 154 | - | - | - |
Deep-Palm: 0.02
|
|
| 164 | - | - | - |
Deep-Palm: 0.02
|
|
| 170 | - | - | - |
Deep-Palm: 0.02
|
|
| 173 | - | - | - |
Deep-Palm: 0.02
|
|
| 179 | - | - | - |
Deep-Palm: 0.02
|
|
| 214 | - | - | - |
Deep-Palm: 0.53
|
|
| 296 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
PC3
Specificity: 0.400
2/2 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
1
U937 cell
Specificity: 0.200
1/1 (100.0%)
1
HUVECs
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 89 | C → C | 0.002427 | SNP | Silent | BLCA |
| 89 | C → C | 0.008130 | SNP | Silent | THYM |
| 132 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |