Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UBR2 | CTSZ | Cathepsin Z (EC 3.4.18.1) (Cathepsin … | Homo sapiens (Human) | 303 aa |
Protein Details: Q9UBR2 (CTSZ)
Protein Information
| Accession | Q9UBR2 |
|---|---|
| Protein Names | Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) |
| Gene Symbol | CTSZ |
| Organism | Homo sapiens (Human) |
| Length | 303 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
2
PC3 cells
Specificity: 0.071
2/4 (50.0%)
1
U937 cells
Specificity: 0.036
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.036
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MARRGPGWRP11LLLLVLLAGA21AQGGLYFRRG31QTCYRPLRGD41GLAPLGRSTY
51-10051PRPHEYLSPA61DLPKSWDWRN71VDGVNYASIT81RNQHIPQYCG91SCWAHASTSA
101-150101MADRINIKRK111GAWPSTLLSV121QNVIDCGNAG131SCEGGNDLSV141WDYAHQHGIP
151-200151DETCNNYQAK161DQECDKFNQC171GTCNEFKECH181AIRNYTLWRV191GDYGSLSGRE
201-250201KMMAEIYANG211PISCGIMATE221RLANYTGGIY231AEYQDTTYIN241HVVSVAGWGI
251-300251SDGTEYWIVR261NSWGEPWGER271GWLRIVTSTY281KDGKGARYNL291AIEEHCTFGD
301-303301PIV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 33 | Prediction (Low) | - | - |
| 296 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 89 | C → C | 0.002427 | SNP | Silent | BLCA |
| 89 | C → C | 0.008130 | SNP | Silent | THYM |
| 132 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |