Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UDT1 | RHBDD2 | Rhomboid domain containing 2 (Supported … | Homo sapiens (Human) | 79 aa |
Protein Details: Q9UDT1 (RHBDD2)
Protein Information
| Accession | Q9UDT1 |
|---|---|
| Protein Names | Rhomboid domain containing 2 (Supported by Human ESTs AA017424.1 (NID:g1479799), H85906.1 (NID:g1067485)) |
| Gene Symbol | RHBDD2 |
| Organism | Homo sapiens (Human) |
| Length | 79 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAASGPGCRS11WCLCPEVPSA21TFFTALLSLL31VSGPRLFLLQ41QPLAPSGLTL
51-7951KSEALRNWQA61TMEGGVRITA71EETGTQSVK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.02
|
| 12 | - | - | - |
Deep-Palm: 0.11
|
|
| 14 | - | - | - |
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
PC3
Specificity: 0.600
3/3 (100.0%)
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 95 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 325 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |