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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9UG63 ABCF2 ATP-binding cassette sub-family F member … Homo sapiens (Human) 623 aa

Protein Details: Q9UG63 (ABCF2)

Protein Information
AccessionQ9UG63
Protein NamesATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2)
Gene SymbolABCF2
OrganismHomo sapiens (Human)
Length623 aa
IsoformsNo isoforms
Related PMIDs 29733200 31382980
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPSDLAKKKA11AKKKEAAKAR21QRPRKGHEEN31GDVVTEPQVA41EKNEANGRET
51-10051TEVDLLTKEL61EDFEMKKAAA71RAVTGVLASH81PNSTDVHIIN91LSLTFHGQEL
101-150101LSDTKLELNS111GRRYGLIGLN121GIGKSMLLSA131IGKREVPIPE141HIDIYHLTRE
151-200151MPPSDKTPLH161CVMEVDTERA171MLEKEAERLA181HEDAECEKLM191ELYERLEELD
201-250201ADKAEMRASR211ILHGLGFTPA221MQRKKLKDFS231GGWRMRVALA241RALFIRPFML
251-300251LLDEPTNHLD261LDACVWLEEE271LKTFKRILVL281VSHSQDFLNG291VCTNIIHMHN
301-350301KKLKYYTGNY311DQYVKTRLEL321EENQMKRFHW331EQDQIAHMKN341YIARFGHGSA
351-400351KLARQAQSKE361KTLQKMMASG371LTERVVSDKT381LSFYFPPCGK391IPPPVIMVQN
401-450401VSFKYTKDGP411CIYNNLEFGI421DLDTRVALVG431PNGAGKSTLL441KLLTGELLPT
451-500451DGMIRKHSHV461KIGRYHQHLQ471EQLDLDLSPL481EYMMKCYPEI491KEKEEMRKII
501-550501GRYGLTGKQQ511VSPIRNLSDG521QKCRVCLAWL531AWQNPHMLFL541DEPTNHLDIE
551-600551TIDALADAIN561EFEGGMMLVS571HDFRLIQQVA581QEIWVCEKQT591ITKWPGDILA
601-623601YKEHLKSKLV611DEEPQLTKRT621HNV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
161 - - -
Deep-Palm: 0.84
186 - - -
Deep-Palm: 0.98
264 - - -
Deep-Palm: 0.97
292 - - -
Deep-Palm: 0.68
388 - - -
GPS-Palm: 0.82
Deep-Palm: 0.71
411 - - -
GPS-Palm: 0.66
Deep-Palm: 0.38
486 - - -
Deep-Palm: 0.91
523 - - -
GPS-Palm: 0.77
Deep-Palm: 0.65
526 - - -
GPS-Palm: 0.88
Deep-Palm: 0.72
586 - - -
GPS-Palm: 0.88
Deep-Palm: 0.63
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
1
HAP1 cell
Specificity: 0.333
1/1 (100.0%)
1
U937 cell
Specificity: 0.333
1/1 (100.0%)
1
293T cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
161 C → C 0.001887 SNP Silent UCEC
195 R → C 0.002288 SNP Missense Mutation STAD
195 R → C 0.001887 SNP Missense Mutation UCEC
223 R → C 0.002506 SNP Missense Mutation COAD
284 S → C 0.001887 SNP Missense Mutation UCEC
292 C → S 0.001764 SNP Missense Mutation LUAD