Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UI42 | CPA4 | Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase … | Homo sapiens (Human) | 421 aa |
Protein Details: Q9UI42 (CPA4)
Protein Information
| Accession | Q9UI42 |
|---|---|
| Protein Names | Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) |
| Gene Symbol | CPA4 |
| Organism | Homo sapiens (Human) |
| Length | 421 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRWILFIGAL11IGSSICGQEK21FFGDQVLRIN31VRNGDEISKL41SQLVNSNNLK
51-10051LNFWKSPSSF61NRPVDVLVPS71VSLQAFKSFL81RSQGLEYAVT91IEDLQALLDN
101-150101EDDEMQHNEG111QERSSNNFNY121GAYHSLEAIY131HEMDNIAADF141PDLARRVKIG
151-200151HSFENRPMYV161LKFSTGKGVR171RPAVWLNAGI181HSREWISQAT191AIWTARKIVS
201-250201DYQRDPAITS211ILEKMDIFLL221PVANPDGYVY231TQTQNRLWRK241TRSRNPGSSC
251-300251IGADPNRNWN261ASFAGKGASD271NPCSEVYHGP281HANSEVEVKS291VVDFIQKHGN
301-350301FKGFIDLHSY311SQLLMYPYGY321SVKKAPDAEE331LDKVARLAAK341ALASVSGTEY
351-400351QVGPTCTTVY361PASGSSIDWA371YDNGIKFAFT381FELRDTGTYG391FLLPANQIIP
401-421401TAEETWLGLK411TIMEHVRDNL421Y
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 16 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.79
|
|
| 250 | - | - | - |
Deep-Palm: 0.60
|
|
| 273 | - | - | - |
Deep-Palm: 0.33
|
|
| 356 | - | - | - |
Deep-Palm: 0.75
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Jurkat T cell
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 230 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 238 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |