Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9UKM7 MAN1B1; UNQ747/PRO1477 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC … Homo sapiens (Human) 699 aa

Protein Details: Q9UKM7 (MAN1B1)

Protein Information
Accession Q9UKM7
Protein Names Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)
Gene Symbol MAN1B1; UNQ747/PRO1477
Organism Homo sapiens (Human)
Length 699 aa
Isoforms No isoforms
Related PMIDs 24357059 26111759 29575903 31251020 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.766
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.766
36/46 (78.3%)
5
Jurkat T cells
Specificity: 0.106
5/25 (20.0%)
3
PC3 cells
Specificity: 0.064
3/4 (75.0%)
1
HeLa cells
Specificity: 0.021
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.021
1/2 (50.0%)
1
Liver membrane
Specificity: 0.021
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAACEGRRSG11ALGSSQSDFL21TPPVGGAPWA31VATTVVMYPP41PPPPPHRDFI
51-10051SVTLSFGENY61DNSKSWRRRS71CWRKWKQLSR81LQRNMILFLL91AFLLFCGLLF
101-150101YINLADHWKA111LAFRLEEEQK121MRPEIAGLKP131ANPPVLPAPQ141KADTDPENLP
151-200151EISSQKTQRH161IQRGPPHLQI171RPPSQDLKDG181TQEEATKRQE191APVDPRPEGD
201-250201PQRTVISWRG211AVIEPEQGTE221LPSRRAEVPT231KPPLPPARTQ241GTPVHLNYRQ
251-300251KGVIDVFLHA261WKGYRKFAWG271HDELKPVSRS281FSEWFGLGLT291LIDALDTMWI
301-350301LGLRKEFEEA311RKWVSKKLHF321EKDVDVNLFE331STIRILGGLL341SAYHLSGDSL
351-400351FLRKAEDFGN361RLMPAFRTPS371KIPYSDVNIG381TGVAHPPRWT391SDSTVAEVTS
401-450401IQLEFRELSR411LTGDKKFQEA421VEKVTQHIHG431LSGKKDGLVP441MFINTHSGLF
451-500451THLGVFTLGA461RADSYYEYLL471KQWIQGGKQE481TQLLEDYVEA491IEGVRTHLLR
501-550501HSEPSKLTFV511GELAHGRFSA521KMDHLVCFLP531GTLALGVYHG541LPASHMELAQ
551-600551ELMETCYQMN561RQMETGLSPE571IVHFNLYPQP581GRRDVEVKPA591DRHNLLRPET
601-650601VESLFYLYRV611TGDRKYQDWG621WEILQSFSRF631TRVPSGGYSS641INNVQDPQKP
651-699651EPRDKMESFF661LGETLKYLFL671LFSDDPNLLS681LDAYVFNTEA691HPLPIWTPA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
4 Prediction (High) - -
71 Prediction (Medium) - -
527 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
249 R → C 0.002288 SNP Missense Mutation STAD
265 R → C 0.003460 SNP Missense Mutation CESC
281 F → C 0.002545 SNP Missense Mutation GBM
502 S → C 0.001969 SNP Missense Mutation HNSC
619 W → C 0.001014 SNP Missense Mutation BRCA