Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UNK0 | STX8 | Syntaxin-8 | Homo sapiens (Human) | 236 aa |
Protein Details: Q9UNK0 (STX8)
Protein Information
| Accession | Q9UNK0 |
|---|---|
| Protein Names | Syntaxin-8 |
| Gene Symbol | STX8 |
| Organism | Homo sapiens (Human) |
| Length | 236 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 25914232 26111759 29733200 31251020 31382980 32651440 32944167 33636221 36430497 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.557
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
39
LNCaP cells
Specificity: 0.557
39/46 (84.8%)
13
Jurkat T cells
Specificity: 0.186
13/25 (52.0%)
4
T cells
Specificity: 0.057
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.057
4/10 (40.0%)
3
PC3 cells
Specificity: 0.043
3/4 (75.0%)
2
DU145 cells
Specificity: 0.029
2/2 (100.0%)
2
CEMx174 cells
Specificity: 0.029
2/3 (66.7%)
1
U937 cells
Specificity: 0.014
1/1 (100.0%)
1
Cerebral cortex
Specificity: 0.014
1/4 (25.0%)
1
Liver membrane
Specificity: 0.014
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAPDPWFSTY11DSTCQIAQEI21AEKIQQRNQY31ERKGEKAPKL41TVTIRALLQN
51-10051LKEKIALLKD61LLLRAVSTHQ71ITQLEGDRRQ81NLLDDLVTRE91RLLLASFKNE
101-150101GAEPDLIRSS111LMSEEAKRGA121PNPWLFEEPE131ETRGLGFDEI141RQQQQKIIQE
151-200151QDAGLDALSS161IISRQKQMGQ171EIGNELDEQN181EIIDDLANLV191ENTDEKLRNE
201-236201TRRVNMVDRK211SASCGMIMVI221LLLLVAIVVV231AVWPTN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 14 | Prediction (Medium) | - | - |
| 214 | DBPTM SWISSPALM Prediction (Low) | SNARE domain | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 198 | R → C | 0.005013 | SNP | Missense Mutation | COAD |
| 198 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 198 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |