Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UNK9 | ANGEL1; KIAA0759 | Protein angel homolog 1 | Homo sapiens (Human) | 670 aa |
Protein Details: Q9UNK9 (ANGEL1)
Protein Information
| Accession | Q9UNK9 |
|---|---|
| Protein Names | Protein angel homolog 1 |
| Gene Symbol | ANGEL1; KIAA0759 |
| Organism | Homo sapiens (Human) |
| Length | 670 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.949
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.949
37/46 (80.4%)
2
PC3 cells
Specificity: 0.051
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIASCLCYLL11LPATRLFRAL21SDAFFTCRKN31VLLANSSSPQ41VEGDFAMAPR
51-10051GPEQEECEGL61LQQWREEGLS71QVLSTASEGP81LIDKGLAQSS91LALLMDNPGE
101-150101ENAASEDRWS111SRQLSDLRAA121ENLDEPFPEM131LGEEPLLEVE141GVEGSMWAAI
151-200151PMQSEPQYAD161CAALPVGALA171TEQWEEDPAV181LAWSIAPEPV191PQEEASIWPF
201-250201EGLGQLQPPA211VEIPYHEILW221REWEDFSTQP231DAQGLKAGDG241PQFQFTLMSY
251-300251NILAQDLMQQ261SSELYLHCHP271DILNWNYRFV281NLMQEFQHWD291PDILCLQEVQ
301-350301EDHYWEQLEP311SLRMMGFTCF321YKRRTGCKTD331GCAVCYKPTR341FRLLCASPVE
351-400351YFRPGLELLN361RDNVGLVLLL371QPLVPEGLGQ381VSVAPLCVAN391THILYNPRRG
401-450401DVKLAQMAIL411LAEVDKVARL421SDGSHCPIIL431CGDLNSVPDS441PLYNFIRDGE
451-500451LQYHGMPAWK461VSGQEDFSHQ471LYQRKLQAPL481WPSSLGITDC491CQYVTSCHPK
501-550501RSERRKYGRD511FLLRFRFCSI521ACQRPVGLVL531MEGVTDTKPE541RPAGWAESVL
551-600551EEDASELEPA561FSRTVGTIQH571CLHLTSVYTH581FLPQRGRPEV591TTMPLGLGMT
601-650601VDYIFFSAES611CENGNRTDHR621LYRDGTLKLL631GRLSLLSEEI641LWAANGLPNP
651-670651FCSSDHLCLL661ASFGMEVTAP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 5 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903 |
| 7 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903 |
| 27 | Experimental Prediction (High) | - | 37611173 |
| 319 | Prediction (High) | - | - |
| 327 | Prediction (Low) | - | - |
| 332 | Prediction (Medium) | - | - |
| 335 | Prediction (High) | - | - |
| 345 | Prediction (Medium) | - | - |
| 426 | Prediction (Medium) | - | - |
| 497 | Prediction (Low) | - | - |
| 518 | Prediction (High) | - | - |
| 522 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 109 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 110 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 265 | Y → C | 0.019608 | SNP | Missense Mutation | CHOL |
| 327 | C → Lfs*7 | 0.002294 | INS | Nonsense Mutation | OV |
| 497 | C → C | 0.001887 | SNP | Silent | UCEC |
| 505 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 505 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 518 | C → Y | 0.006993 | SNP | Missense Mutation | LAML |
| 561 | F → Cfs*50 | 0.001969 | INS | Frame Shift Ins | HNSC |
| 585 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 611 | C → R | 0.002294 | SNP | Missense Mutation | OV |
| 622 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |