Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9UNN8 | PROCR | Endothelial protein C receptor (Activated … | Homo sapiens (Human) | 238 aa |
Protein Details: Q9UNN8 (PROCR)
Protein Information
| Accession | Q9UNN8 |
|---|---|
| Protein Names | Endothelial protein C receptor (Activated protein C receptor) (APC receptor) (Endothelial cell protein C receptor) (CD antigen CD201) |
| Gene Symbol | PROCR |
| Organism | Homo sapiens (Human) |
| Length | 238 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLTTLLPILL11LSGWAFCSQD21ASDGLQRLHM31LQISYFRDPY41HVWYQGNASL
51-10051GGHLTHVLEG61PDTNTTIIQL71QPLQEPESWA81RTQSGLQSYL91LQFHGLVRLV
101-150101HQERTLAFPL111TIRCFLGCEL121PPEGSRAHVF131FEVAVNGSSF141VSFRPERALW
151-200151QADTQVTSGV161VTFTLQQLNA171YNRTRYELRE181FLEDTCVQYV191QKHISAENTK
201-238201GSQTSRSYTS211LVLGVLVGSF221IIAGVAVGIF231LCTGGRRC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | Endothelial protein C receptor | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.98
|
|
| 114 | - | - | - |
Deep-Palm: 0.93
|
|
| 118 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.95
|
|
| 186 | - | - | - |
Deep-Palm: 0.52
|
|
| 232 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.04
|
|
| 238 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
1
EC cell
Specificity: 0.333
1/1 (100.0%)
1
heart
Specificity: 0.333
1/1 (100.0%)
1
HUVECs
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 114 | C → S | 0.002976 | SNP | Missense Mutation | KIRC |
| 173 | R → C | 0.003460 | SNP | Missense Mutation | CESC |