Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9WTL7 | Lypla2 | Acyl-protein thioesterase 2 (APT-2) (EC … | Mus musculus (Mouse) | 231 aa |
Protein Details: Q9WTL7 (Lypla2)
Protein Information
| Accession | Q9WTL7 |
|---|---|
| Protein Names | Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase 2) (Lysophospholipase II) (LPL-II) (LysoPLA II) (mLyso II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) |
| Gene Symbol | Lypla2 |
| Organism | Mus musculus (Mouse) |
| Length | 231 aa |
| Isoforms | No isoforms |
| Related PMIDs | 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCGNTMSVPL11LTDAATVSGA21ERETAAVIFL31HGLGDTGHSW41ADALSTIRLP
51-10051HVKYICPHAP61RIPVTLNMKM71VMPSWFDLMG81LSPDAPEDEA91GIKKAAENIK
101-150101ALIEHEMKNG111IPANRIVLGG121FSQGGALSLY131TALTCPHPLA141GIVALSCWLP
151-200151LHRNFPQAAN161GSAKDLAILQ171CHGELDPMVP181VRFGALTAEK191LRTVVTPARV
201-231201QFKTYPGVMH211SSCPQEMAAV221KEFLEKLLPP231V
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
| 56 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.66
|
|
| 135 | - | - | - |
Deep-Palm: 0.93
|
|
| 147 | - | - | - |
Deep-Palm: 0.91
|
|
| 171 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.89
|
|
| 213 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Liver
Specificity: 0.095
2/2 (100.0%)
1
Testis
Specificity: 0.048
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.857
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.