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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9WUP4 Srd5a3 Polyprenal reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid … Mus musculus (Mouse) 330 aa

Protein Details: Q9WUP4 (Srd5a3)

Protein Information
AccessionQ9WUP4
Protein NamesPolyprenal reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)
Gene SymbolSrd5a3
OrganismMus musculus (Mouse)
Length330 aa
IsoformsNo isoforms
Related PMIDs 28526873 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGWAGFELS11ALNPLRTLWL21ALAAAFLFAL31LLQLAPARLL41PSCALFQDLL
51-10051RYGKTKQSGS61RRPAVCRAFD71VPKRYFSHFY81VISVVWNGSL91LWLLSQSLFL
101-150101GAPFPNWLSA111LLRTLGATQF121QALEMESKAS131RMPAAELALS141AFLVLVFLWV
151-200151HSLRRLFECF161YVSVFSNAAI171HVVQYCFGLV181YYVLVGLTVL191SQVPMDDKNV
201-250201YVLGKNLLIQ211ARWFHILGMV221MFFWSSAHQY231KCHVILSNLR241RNKKGVVIHC
251-300251QHRIPFGDWF261EYVSSANYLA271ELMIYISMAV281TFGLHNLTWW291LVVTYVFSSQ
301-330301ALSAFFNHKF311YRSTFVSYPK321HRKAFLPFLF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
43 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.95
Deep-Palm: 0.98
66 - - -
Deep-Palm: 0.69
159 - - -
Deep-Palm: 0.33
176 - - -
Deep-Palm: 0.60
232 - - -
Deep-Palm: 0.34
250 - - -
Deep-Palm: 0.77
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine